Magnetic resonance imaging for diagnosis and assessment of cartilage defect repairs
Magnetic resonance imaging for diagnosis and assessment of cartilage defect repairs
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DOI：
10.1016/j.injury.2008.01.043
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发表时间：
2008-04-01
影响因子：
2.5
通讯作者：
Trattnig, Siegfried
中科院分区：
文献类型：
--
作者：
Marlovits, Stefan;Mamisch, Tallal Charles;Trattnig, Siegfried
临床磁共振成像（MRI）是关节软骨缺损的非侵入性评估和软骨修复手术随访的首选方法。软骨敏感序列和高空间分辨率技术的使用使得即使在疾病的早期阶段也能够评估软骨形态，以及评估软骨修复。关节软骨与邻近结构之间的高对比度序列，如脂肪抑制的三维扰相梯度回波序列和快速自旋回波序列，是评估关节软骨内病变和表面缺损的准确和可靠的序列。这些序列也可以在合理的检查时间内一起执行。除了形态学，新的MRI技术提供了深入了解关节软骨和软骨修复组织的生化组成。这些技术能够诊断早期软骨退化，并有助于监测各种手术和非手术软骨修复疗法的效果和结果。
Clinical magnetic resonance imaging (MRI) is the method of choice for the non-invasive evaluation of articular cartilage defects and the follow-up of cartilage repair procedures. The use of cartilage-sensitive sequences and a high spatial-resolution technique enables the evaluation of cartilage morphology even in the early stages of disease, as well as assessment of cartilage repair. Sequences that offer high contrast between articular cartilage and adjacent structures, such as the fat-suppressed, 3-dimensional, spoiled gradient-echo sequence and the fast spin-echo sequence, are accurate and reliable for evaluating intrachondral lesions and surface defects of articular cartilage. These sequences can also be performed together in reasonable examination times. In addition to morphology, new MRI techniques provide insight into the biochemical composition of articular cartilage and cartilage repair tissue. These techniques enable the diagnosis of early cartilage degeneration and help to monitor the effect and outcome of various surgical and non-surgical cartilage repair therapies.