SEROPREVALENCE OF ANTIBODIES TO HUMAN HERPESVIRUSES IN ENGLAND AND HONG-KONG
SEROPREVALENCE OF ANTIBODIES TO HUMAN HERPESVIRUSES IN ENGLAND AND HONG-KONG
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DOI：
10.1002/jmv.1890430117
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发表时间：
1994-05-01
影响因子：
12.7
通讯作者：
NG, MH
中科院分区：
文献类型：
--
作者：
KANGRO, HO;OSMAN, HK;NG, MH
英国和香港的疱疹病毒抗体与年龄相关的流行率进行了比较。对来自英国的327份血清和来自香港的266份血清进行了单纯疱疹病毒(HSV)、水痘带状疱疹病毒(VZV)、EB病毒(EBV)、巨细胞病毒(CMV)和人类疱疹病毒6(HHV-6)的抗体检测。疱疹病毒感染在两个国家都很常见，但一般较早获得，在香港更为普遍。香港超过90%的儿童在8岁前感染了VZV、EBV和HHV-6。在两个国家，单纯疱疹病毒和巨细胞病毒是儿童感染最少的两种病毒，尽管香港有30%-40%的婴儿在出生后第一年就被感染了。在英国队列中，CMV感染在整个童年时期都很少见。过度挤迫和提早入读幼稚园，可能有助更有效和更早地在香港传播疱疹病毒。特别是巨细胞病毒的高流行率，可能会对香港年轻孕妇和器官移植受者的管理产生影响。(C)1994年Wiley-Liss，Inc.
The age-related prevalence of antibodies to herpesviruses was compared in England and Hong Kong. Altogether 327 sera from England and 266 sera from Hong Kong were tested for antibodies to herpes simplex virus (HSV), varicella-zoster virus (VZV), Epstein-Barr virus (EBV), cytomegalovirus (CMV), and human herpesvirus 6 (HHV-6). Herpesvirus infections were common in both countries but generally were acquired earlier and were more prevalent in Hong Kong. Over 90% of children in Hong Kong were infected with VZV, EBV, and HHV-6 by 8 years of age. HSV and CMV were the least prevalent childhood infections in both countries, although, 30-40% of babies in Hong Kong became infected during the first year of life. CMV infections were rare throughout childhood in the English cohort. Overcrowding and early attendance at kindergarten may aid more efficient and earlier transmission of herpesvirus in Hong Kong. The high prevalence of CMV in particular may have implications for the management of young pregnant women and organ transplant recipients in Hong Kong. (C) 1994 Wiley-Liss, Inc.