Trends in the incidences of acute myocardial infarction in coastal and inland areas in Japan: The Yamagata AMI Registry.
Trends in the incidences of acute myocardial infarction in coastal and inland areas in Japan: The Yamagata AMI Registry.
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日本沿海和内陆地区急性心肌梗死发病率趋势：山形 AMI 登记处。
DOI：
10.1016/j.jjcc.2015.08.015
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发表时间：
2015
期刊：
影响因子：
--
通讯作者：
Kubota I.
中科院分区：
文献类型：
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作者：
Wanezaki M;Watanabe T;Nishiyama S;Hirayama A;Arimoto T;Takahashi H;Shishido T;Miyamoto T;Kawasaki R;Fukao A;Kubota I.
研究背景日本急性心肌梗死（AMI）的发病率存在地区差异。本研究的目的是调查沿海和内陆地区之间AMI发病率和血脂异常的地区差异趋势。方法我们调查了5325例首次AMI患者的AMI发病率和危险因素的趋势，这些患者居住在沿海地区（n= 1817），内陆农村地区（n= 1959），或城市内陆地区（n= 1549）的1994-2002年和2003-2010年期间，使用的数据从山形AMI Registry.ResultsPatients在沿海地区的显着年龄比那些在农村和城市内陆地区，血脂异常的患病率较低。在两个观察期内，沿海和农村内陆地区AMI的年龄校正发病率显著低于城市内陆地区（男性：43.3、42.2和51.3/105人年;女性：17.4、20.0和23.7/105人年）。由于沿海地区年轻男性AMI发病率大幅增加，而城市内陆地区老年女性AMI发病率下降，因此在2003-2010年期间，未观察到两种性别的AMI年龄校正发病率的显著区域差异。在沿海地区的男性AMI发病率的增加与血脂异常的患病率增加。ConclusionThere不再有任何区域差异观察AMI发病率，这被认为是与血脂异常增加，特别是在沿海地区。
BackgroundIt has been reported that there are regional differences in the incidence of acute myocardial infarction (AMI) in Japan. The purpose of this study was to investigate trends in regional differences in AMI incidence and dyslipidemia between coastal and inland areas.MethodsWe investigated trends in AMI incidence and risk factors in 5325 first-ever AMI patients residing in a coastal area (n= 1817), a rural inland area (n= 1959), or an urban inland area (n= 1549) for the periods 1994–2002, and 2003–2010, using data from the Yamagata AMI Registry.ResultsPatients in the coastal area were significantly older than those in rural and urban inland areas and had a lower prevalence of dyslipidemia. The age-adjusted incidence rate of AMI was significantly lower in coastal and rural inland areas patients than those from urban inland area (males: 43.3, 42.2, and 51.3/105person-years; females: 17.4, 20.0, and 23.7/105person-years, respectively) during 2 observation periods. Due to a large increase in AMI incidence in younger males of the coastal area and a decrease in AMI incidence in late elderly females of the urban inland area, no significant regional differences in the age-adjusted incidence rates of AMI were observed during the 2003–2010 period in both genders. The increase in AMI incidence in males in the coastal area was associated with an increasing prevalence of dyslipidemia.ConclusionThere were no longer any regional differences observed in AMI incidence, which was considered to be associated with increased dyslipidemia especially in the coastal area.