Hydrogenation of butane-2,3-dione with heterogeneous cinchona modified platinum catalysts: a combination of an enantioselective reaction and kinetic resolution
Hydrogenation of butane-2,3-dione with heterogeneous cinchona modified platinum catalysts: a combination of an enantioselective reaction and kinetic resolution
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DOI：
10.1039/a801390j
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发表时间：
1998
影响因子：
4.9
通讯作者：
M. Studer;H. Blaser;V. Okafor
中科院分区：
文献类型：
--
作者：
M. Studer;H. Blaser;V. Okafor
通过 Pt/Al2O3 金鸡纳催化加氢丁烷-2,3-二酮，通过对映选择性加氢和动力学拆分相结合，获得了 (R)-3-羟基丁-2-酮，尽管产率较低，但产率为 85–90%。
(R)-3-Hydroxybutan-2-one was obtained with 85–90% ee albeit in low yield by the Pt/Al2O3 cinchona catalyzed hydrogenation of butane-2,3-dione by a combination of enantioselective hydrogenation and kinetic resolution.