The effect of age, sex, obesity and posture an upper airway size
The effect of age, sex, obesity and posture an upper airway size
复制标题
DOI：
10.1183/09031936.97.10092087
复制
发表时间：
1997-09-01
影响因子：
24.3
通讯作者：
Douglas, NJ
中科院分区：
文献类型：
--
作者：
Martin, SE;Mathur, R;Douglas, NJ
睡眠呼吸暂停低通气综合征(SAHS)患者多为中年男性。由于年龄和性别对上呼吸道口径的影响存在相互矛盾的数据，我们检验了年龄和性别增加易导致正常受试者上呼吸道狭窄的假设。我们用声反射技术测量了60名男性和54名女性(中位数35岁，范围16-74岁)坐着和仰卧时的上呼吸道口径。除口咽交界处(OPJ)外，所有上呼吸道尺寸在男性和女性中都随着年龄的增长而减小(r>；-0.24，p小于或等于0.05)，而仰卧(r(2)>；0.06)。男性卧床时OPJ的气道面积变化较大(平均(SEM)0.5(0.1)，0.2(0.1)cm(2)；p
Most patients with sleep apnoea/hypopnoea syndrome (SAHS) are middle-aged men. As there are conflicting data on the effects of age and gender on upper airway calibre, we tested the hypothesis that increasing age and the male sex predispose to upper airway narrowing in normal subjects.We measured upper airway calibre using acoustic reflection in 60 men and 54 women (median 35, range 16-74 yrs) both seated and supine.All upper airway dimensions, except oropharyngeal junction (OPJ), decreased with increasing age in both men and women (r>-0.24, p less than or equal to 0.05) while supine (r(2)>0.06). Men had greater changes in airway area at OPJ on lying down (mean (SEM) 0.5 (0.1), 0.2 (0.1) cm(2); p