MOLECULAR-WEIGHT CHANGES IN POLYMER EROSION
MOLECULAR-WEIGHT CHANGES IN POLYMER EROSION
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DOI：
10.1023/a:1015801216466
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发表时间：
1992-10-01
影响因子：
3.7
通讯作者：
LANGER, R
中科院分区：
文献类型：
--
作者：
DEMANUELE, A;HILL, J;LANGER, R
本文研究了聚合物分子量对由1，3-双（对羧基苯氧基）丙烷（CPP）和癸二酸（SA）组成的聚酸酐共聚物基体在水溶液中腐蚀的影响。侵蚀剖面特征性地显示出诱导期，在此期间侵蚀速率相对较慢。该时间段的长度取决于聚合物的初始分子量。诱导期可以表征为聚合物分子量发生快速降低的时间，该时间段的结束与聚合物分子量降低至低于约5000（MW）的值所需的时间相关。
We report a study of the effects of polymer molecular weight on the erosion of polyanhydride copolymer matrices composed of 1,3-bis(p-carboxyphenoxy)-propane (CPP) and sebacic acid (SA) in aqueous solution. The erosion profile characteristically displays an induction period during which the erosion rate is relatively slow. The length of this period depends on the initial molecular weight of the polymer. The induction period may be characterized as a time during which a rapid decrease in polymer molecular weight occurs, the end of this period correlating with the time required for the polymer molecular weight to decrease to below a value of approximately 5000 (MW).