Improved pulmonary function and exercise tolerance despite persistent pulmonary fibrosis over 1 year after severe COVID-19 infection.

Improved pulmonary function and exercise tolerance despite persistent pulmonary fibrosis over 1 year after severe COVID-19 infection.
复制标题

尽管严重感染 COVID-19 后一年多仍出现持续性肺纤维化,但肺功能和运动耐量仍得到改善。

DOI:
10.1136/thorax-2023-220370
复制
发表时间:
2024
期刊:
影响因子:
10
通讯作者:
Garcia,ChristineKim
Garcia,ChristineKim
中科院分区:
医学1区
文献类型:
--
作者:
McGroder,ClaireF;Salvatore,MaryM;D'Souza,BelindaM;Hoffman,EricA;Baldwin,MatthewR;Garcia,ChristineKim

文献摘要

参考文献

相似文献

我们对住院15个月后第一波大流行中104名多民族COVID-19重症幸存者进行了一项前瞻性单中心队列研究。在4个月和15个月时进行评估的患者中,磨玻璃混浊的改善与纤维化网的恶化相关。尽管纤维化模式的患病率很高(64%),但肺功能、握力、6分钟步行距离和虚弱都恢复了正常。总的来说,呼吸困难、咳嗽和乏力在15个月时没有改善,也与肺功能或影像学纤维化无关,提示非呼吸病因。监测持续的,通常是亚临床的,纤维化间质异常将需要确定其未来发展的潜力。
We conducted a prospective single-centre cohort study of 104 multi-ethnic severe COVID-19 survivors from the first wave of the pandemic 15 months after hospitalisation. Of those who were assessed at 4 and 15 months, improvement of ground glass opacities correlated with worsened fibrotic reticulations. Despite a high prevalence of fibrotic patterns (64%), pulmonary function, grip strength, 6 min walk distance and frailty normalised. Overall, dyspnoea, cough and exhaustion did not improve and were not correlated with pulmonary function or radiographic fibrosis at 15 months, suggesting non-respiratory aetiologies. Monitoring persistent, and often subclinical, fibrotic interstitial abnormalities will be needed to determine their potential for future progression.
DOI: 10.1126/science.1978757
发表时间: 1990-11-30
期刊: SCIENCE
影响因子: 56.9
作者:
MALKIN, D;LI, FP;FRIEND, SH
通讯作者: FRIEND, SH
儿童和年轻人常见的中枢神经系统肿瘤遗传信息丢失
DOI: --
发表时间: 1990
期刊: Genes, Chromosomes and Cancer
影响因子: --
作者:
C. James;Ju He;E. Carlbom;T. Mikkelsen;P. Ridderheim;W. Cavenee;V. Collins
通讯作者: V. Collins
DOI: --
发表时间: 1988-10
期刊: Cancer research
影响因子: 11.2
作者:
C. James;E. Carlbom;J. Dumanski;Marc F. Hansen;Magnus Nordenskjöld;V. Collins;W. Cavenee
通讯作者: C. James;E. Carlbom;J. Dumanski;Marc F. Hansen;Magnus Nordenskjöld;V. Collins;W. Cavenee
DOI: --
发表时间: 1990
影响因子: 4.6
作者:
J. Boyd;J. Barrett
通讯作者: J. Barrett
DOI: 10.1126/science.1905840
发表时间: 1991-07-05
期刊: SCIENCE
影响因子: 56.9
作者:
HOLLSTEIN, M;SIDRANSKY, D;HARRIS, CC
通讯作者: HARRIS, CC