Improved pulmonary function and exercise tolerance despite persistent pulmonary fibrosis over 1 year after severe COVID-19 infection.
Improved pulmonary function and exercise tolerance despite persistent pulmonary fibrosis over 1 year after severe COVID-19 infection.
复制标题
尽管严重感染 COVID-19 后一年多仍出现持续性肺纤维化,但肺功能和运动耐量仍得到改善。
DOI:
10.1136/thorax-2023-220370
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发表时间:
2024
期刊:
影响因子:
10
通讯作者:
Garcia,ChristineKim
中科院分区:
文献类型:
--
作者:
McGroder,ClaireF;Salvatore,MaryM;D'Souza,BelindaM;Hoffman,EricA;Baldwin,MatthewR;Garcia,ChristineKim
We conducted a prospective single-centre cohort study of 104 multi-ethnic severe COVID-19 survivors from the first wave of the pandemic 15 months after hospitalisation. Of those who were assessed at 4 and 15 months, improvement of ground glass opacities correlated with worsened fibrotic reticulations. Despite a high prevalence of fibrotic patterns (64%), pulmonary function, grip strength, 6 min walk distance and frailty normalised. Overall, dyspnoea, cough and exhaustion did not improve and were not correlated with pulmonary function or radiographic fibrosis at 15 months, suggesting non-respiratory aetiologies. Monitoring persistent, and often subclinical, fibrotic interstitial abnormalities will be needed to determine their potential for future progression.
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影响因子:
56.9
作者:
MALKIN, D;LI, FP;FRIEND, SH
通讯作者:
FRIEND, SH
DOI:
--
发表时间:
1990
期刊:
Genes, Chromosomes and Cancer
影响因子:
--
作者:
C. James;Ju He;E. Carlbom;T. Mikkelsen;P. Ridderheim;W. Cavenee;V. Collins
通讯作者:
V. Collins
影响因子:
11.2
作者:
C. James;E. Carlbom;J. Dumanski;Marc F. Hansen;Magnus Nordenskjöld;V. Collins;W. Cavenee
通讯作者:
C. James;E. Carlbom;J. Dumanski;Marc F. Hansen;Magnus Nordenskjöld;V. Collins;W. Cavenee
影响因子:
4.6
作者:
J. Boyd;J. Barrett
通讯作者:
J. Barrett
影响因子:
56.9
作者:
HOLLSTEIN, M;SIDRANSKY, D;HARRIS, CC
通讯作者:
HARRIS, CC