G-quartet, G-quadruplex, and G-wire Regulated by Chemical Stimuli
G-quartet, G-quadruplex, and G-wire Regulated by Chemical Stimuli
复制标题
受化学刺激调节的 G-四联体、G-四联体和 G 线
DOI：
10.1007/978-1-61779-142-0_7
复制
发表时间：
2011
期刊：
影响因子：
--
通讯作者：
N.Sugimoto
中科院分区：
文献类型：
--
作者：
D.Miyoshi;N.Sugimoto
富含鸟嘌呤的DNA广泛分布在人类基因组中，可以折叠成一种称为G线的超分子结构。G线具有作为体外和体内各种应用的功能元件的有前途的特性。在这里，我们描述了G线的制备过程和G线形成的特征。通过化学刺激调节G线形成的程序将有助于体内和体外应用。
Guanine-rich DNA, which is widely distributed in the human genome, can fold into a supramolecular structure called the G-wire. The G-wire possesses promising characteristics as a functional element for various applicationsin vitroandin vivo. Here, we describe the preparative procedures for the G-wire and signatures of G-wire formation. Procedures for the regulation of G-wire formation by chemical stimuli will be useful forin vivoandin vitroapplications.