The relationship between the onset of sweating and vasodilatation in the forearm during body heating
The relationship between the onset of sweating and vasodilatation in the forearm during body heating
复制标题
身体发热时出汗与前臂血管舒张的关系
DOI：
10.1113/jphysiol.1962.sp006918
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发表时间：
1962
期刊：
影响因子：
--
通讯作者：
R. Shanks
中科院分区：
文献类型：
--
作者：
A. Love;R. Shanks
加热寒冷的对象会导致流经人体前臂的血流量增加，但仅限于皮肤循环（Barcroft、Bock、Hensel 和 Kitchin，1955）。它分两个阶段发生，首先是血管收缩张力降低，随后是胆碱能神经活动引起的主动血管舒张（Roddie、Shepherd & Whelan，1957）。据推测，后一种血管舒张机制继发于汗腺活动和血浆激肽（缓激肽）的形成，而不是直接血管神经支配的结果（Fox＆Hilton，1958）。如果缓激肽参与受热受试者前臂血流量的增加，则预计汗腺活动将先于血管舒张。本实验试图准确定义身体加热期间汗腺活动与前臂血流变化的关系。
The increase in blood flow through the human forearm produced by heating a cold subject is confined to the circulation in the skin (Barcroft, Bock, Hensel & Kitchin, 1955). It occurs in two phases, an initial reduction in vasoconstrictor tone followed by an active vasodilatation resulting from the activity of cholinergic nerves (Roddie, Shepherd & Whelan, 1957). It has been postulated that the latter vasodilator mechanism is secondary to sweat-gland activity and the formation of plasma kinin (bradykinin) and does not result from direct vascular innervation (Fox & Hilton, 1958). If bradykinin is involved in the increase in blood flow in the forearm of the heated subject it would be expected that sweat-gland activity would precede the vasodilatation. The present experiments are an attempt to define accurately the relationship of sweat-gland activity to blood-flow changes in the forearm during body heating.