Across the great divide: the plant cell surface continuum.
Across the great divide: the plant cell surface continuum.
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DOI：
10.1016/j.pbi.2014.11.004
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发表时间：
2014-12
影响因子：
9.5
通讯作者：
Joseph Mckenna;A. F. Tolmie;J. Runions
中科院分区：
文献类型：
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作者：
Joseph Mckenna;A. F. Tolmie;J. Runions
植物质膜蛋白在脂质双分子层中不是随机分布的。细胞骨架和细胞壁共同调节质膜蛋白的迁移和结合。膜微结构域将蛋白质组织成功能关联。质膜蛋白具有信号传导和酶促作用。光漂白后荧光恢复（FRAP）可以监测膜蛋白动态。植物细胞壁、细胞质膜和细胞骨架作为一个细胞表面连续体存在。这种细胞器的互连形成了植物细胞和外部环境之间的界面，对于检测各种刺激的存在是重要的。大量的质膜微域被认为在膜定位酶或信号过程中起作用。虽然细胞壁组成的调节是由质膜内的蛋白质决定的，但细胞壁已被证明对质膜蛋白具有锚定作用，从而影响其横向移动。质膜和细胞壁组分之间的相互作用是质膜微域功能的必要条件。肌动蛋白和微管细胞骨架也参与细胞表面连续体的维持和功能。如果我们要了解细胞如何对外部信号作出反应，研究这种机制的细胞器组分之间的相互作用是很重要的。
HighlightsPlant plasma membrane proteins are not randomly distributed within the lipid bilayer.Both cytoskeleton and cell wall regulate plasma membrane protein mobility and association.Membrane microdomains organize proteins into functional associations.Plasma membrane proteins have both signalling and enzymatic roles.Fluorescence Recovery After Photobleaching (FRAP) enables monitoring of membrane protein dynamics.The plant cell wall, plasma membrane and cytoskeleton exist as a cell surface continuum. This interconnection of organelles forms the interface between the plant cell and the external environment and is important for detecting the presence of a diverse range of stimuli. A plethora of plasma membrane microdomains with putative roles in membrane localized enzymatic or signalling processes have been described. While regulation of cell wall composition is defined by proteins within the plasma membrane, the cell wall has been shown to have an anchoring role on plasma membrane proteins which affects their lateral mobility. This interplay between plasma membrane and cell wall components is necessary for plasma membrane microdomain function. Actin and microtubule cytoskeletons are also involved in maintenance and function of the cell surface continuum. Investigation of the interactions between organellar components of this mechanism are important if we are to understand how cells respond to external signals.