GeneAnnot: Interfacing GeneCards with highthroughput gene expression compendia
GeneAnnot: Interfacing GeneCards with highthroughput gene expression compendia
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DOI：
10.1093/bib/4.4.349
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发表时间：
2003-12-01
影响因子：
9.5
通讯作者：
Lancet, Doron
中科院分区：
文献类型：
--
作者：
Chalifa-Caspi, Vered;Shmueli, Orit;Lancet, Doron
微阵列表达结果的解释通常包括大量的工作来鉴定和注释固定在阵列上的基因代表。在本文中，我们描述了我们的自动GeneAnnot系统的使用，它连接Affytron阵列和GeneCards中丰富的人类基因注释。我们解释GeneCards搜索选项和结果显示;详细说明GeneCards中表达信息的呈现，包括我们的全基因组GeneNote项目和外部表达资源;描述GeneAnnot用于评估注释质量和概率特异性的各种参数和显示;并展示如何直接搜索GeneAnnot和GeneNote网站。
The interpretation of microarray expression results often includes extensive efforts to identify and annotate the gene representatives immobilised on the arrays. In this paper we describe the usage of our automatic GeneAnnot system, which links between Affymetrix arrays and the rich human gene annotations available in GeneCards. We explain GeneCards search options and results display; elaborate on the presentation of expression information in GeneCards, including both our whole-genome GeneNote project and external expression resources; describe the various parameters and displays used by GeneAnnot to assess the annotation quality and probeset specificity; and show how to search GeneAnnot and GeneNote websites directly.