ZINC-ABSORPTION IN ADULT HUMANS - THE EFFECT OF IRON FORTIFICATION
ZINC-ABSORPTION IN ADULT HUMANS - THE EFFECT OF IRON FORTIFICATION
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DOI：
10.1079/bjn19950145
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发表时间：
1995-09-01
影响因子：
3.6
通讯作者：
HURRELL, RF
中科院分区：
文献类型：
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作者：
DAVIDSSON, L;ALMGREN, A;HURRELL, RF
通过对单餐进行放射性同位素标记，然后测量摄入后 14 天的 Zn-65 全身保留量，研究了铁强化对 Zn 吸收的影响。健康的成年志愿者参与了这项研究。该研究对断奶麦片、小麦面包和婴儿配方奶粉等经常添加铁的食品进行了评估。以 FeSO4 形式添加的 Fe 量与欧洲和美国商业产品中的水平相似，分别为 200 或 500 mg Fe/kg（断奶麦片）、65 mg Fe/kg（白小麦粉）和 12 mg Fell（婴儿配方奶粉）。为了进行比较，测量了相同受试者在不添加铁的相同测试膳食中的锌吸收量。将添加 Pe 的测试餐中的锌吸收量与未添加铁的测试餐中的锌吸收量进行比较时，没有发现统计学上的显着差异。铁强化膳食与非强化膳食的锌吸收分数分别为 31.1 (SD 11.9) v. 30.7 (SD 7.0)%（断奶谷物；200 mg Fe/kg）、37.7 (SD 16.6) v. 30.2 (SD 9.9)%（断奶谷物；500 mg Fe/kg）、36.5 (SD 14.4) v. 38.2(SD 18.1)%（面包；65 mg Fe/kg 面粉）和 41.6 (SD 8.1) v. 38.9 (SD 14.5)%（婴儿配方奶粉；12 mg Fe/l）。因此，以目前使用的强化水平在食品中添加铁与锌的吸收受损无关，并且食用这些铁强化食品预计不会对锌营养产生负面影响。
The effect of Fe fortification on the absorption of Zn was studied by radioisotopic labelling of single meals, followed by measurements of whole-body retention of Zn-65 at 14 d after intake. Healthy adult volunteers participated in the study. Weaning cereal, wheat bread and infant formula, foods that are all frequently Fe-fortified, were evaluated in the study. The amounts of Fe added as FeSO4 were similar to the levels in commercial products in Europe and the USA, and were 200 or 500 mg Fe/kg (weaning cereal), 65 mg Fe/kg (white wheat flour) and 12 mg Fell (infant formula). For comparison, Zn absorption was measured in the same subjects, from identical test meals containing no added Fe. No statistically significant differences were found when Zn absorption from the Pe-fortified test meals was compared with that from non-Fe-fortified test meals. Fractional Zn-absorption values from Fe-fortified v. non-fortified meals were 31.1 (SD 11.9) v. 30.7 (SD 7.0)% (weaning cereal; 200 mg Fe/kg), 37.7 (SD 16.6) v. 30.2 (SD 9.9)% (weaning cereal; 500 mg Fe/kg), 36.5 (SD 14.4) v. 38.2(SD 18.1)% (bread; 65 mg Fe/kg flour) and 41.6 (SD 8.1) v. 38.9 (SD 14.5)% (infant formula; 12 mg Fe/l). The addition of Fe to foods at the currently used fortification levels was thus not associated with impaired absorption of Zn and the consumption of these Fe-fortified foods would not be expected to have a negative effect on Zn nutrition.