Visual and Non-Visual Navigation in Blind Patients with a Retinal Prosthesis
Visual and Non-Visual Navigation in Blind Patients with a Retinal Prosthesis
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DOI：
10.1371/journal.pone.0134369
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发表时间：
2015-07-30
期刊：
影响因子：
3.7
通讯作者：
Nardini, Marko
中科院分区：
文献类型：
--
作者：
Garcia, Sara;Petrini, Karin;Nardini, Marko
具有正常视力的成年人可以将联合收割机视觉地标和非视觉自运动线索相结合来提高其导航精度。在这里，我们询问了接受视网膜假体治疗的盲人是否也可以在导航时从使用由此产生的新视觉信号和非视觉信息中受益。四名患者（失明15-52岁）植入Argus II视网膜假体（Second Sight Medical Products Inc. Sylmar，CA）和五个年龄匹配的和六个年轻的对照组参与了研究。参与者完成了路径再现和三角形完成导航任务，使用间接的视觉地标和非视觉自我运动线索或非视觉自我运动线索。对照组参与者佩戴的护目镜与Argus II假体的视野和分辨率接近。在这两项任务中，控制参与者在视力下降的情况下导航时表现出更好的精度，而不是没有视力。然而，患者在路径再现任务中使用假体导航时没有表现出类似的改善，但两名患者在三角形完成任务中确实表现出改善。此外，在无视觉导航时，所有患者在两项任务中均表现出比对照组更高的精度。这些结果表明，Argus II视网膜假体可能无法提供足够可靠的视觉信息，以提高患者完成任务的精度，因为他们已经学会依赖非视觉感官。
Human adults with normal vision can combine visual landmark and non-visual self-motion cues to improve their navigational precision. Here we asked whether blind individuals treated with a retinal prosthesis could also benefit from using the resultant new visual signal together with non-visual information when navigating. Four patients (blind for 15-52 years) implanted with the Argus II retinal prosthesis (Second Sight Medical Products Inc. Sylmar, CA), and five age-matched and six younger controls, participated. Participants completed a path reproduction and a triangle completion navigation task, using either an indirect visual landmark and non-visual self-motion cues or non-visual self-motion cues only. Control participants wore goggles that approximated the field of view and the resolution of the Argus II prosthesis. In both tasks, control participants showed better precision when navigating with reduced vision, compared to without vision. Patients, however, did not show similar improvements when navigating with the prosthesis in the path reproduction task, but two patients did show improvements in the triangle completion task. Additionally, all patients showed greater precision than controls in both tasks when navigating without vision. These results indicate that the Argus II retinal prosthesis may not provide sufficiently reliable visual information to improve the precision of patients on tasks, for which they have learnt to rely on non-visual senses.