Clinical implications of benign multiple sclerosis: A 20-year population-based follow-up study
Clinical implications of benign multiple sclerosis: A 20-year population-based follow-up study
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DOI：
10.1002/ana.20197
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发表时间：
2004-08-01
影响因子：
11.2
通讯作者：
Rodriguez, M
中科院分区：
文献类型：
--
作者：
Pittock, SJ;McClelland, RL;Rodriguez, M
2001年，我们随访了1991年奥姆斯特德县多发性硬化（MS）患病率队列的所有患者。我们发现，MS的持续时间越长，残疾程度越低，患者就越有可能保持稳定而不会进展。这对于10年或更长时间内扩展残疾状态量表评分为2或更低的良性MS患者特别有效，这些患者有90%以上的机会保持稳定。这很重要，因为这些患者占整个患病率队列的17%。这些数据应有助于是否开始免疫调节药物的共同治疗决策过程。
In 2001, we followed up all patients from the 1991 Olmsted County Multiple Sclerosis (MS) prevalence cohort. We found that the longer the duration of MS and the lower the disability, the more likely a patient is to remain stable and not progress. This is particularly powerful for patients with benign MS with Expanded Disability Status Scale score of 2 or lower for 10 years or longer who have a greater than 90% chance of remaining stable. This is important because these patients represent 17% of the entire prevalence cohort. These data should assist in the shared therapeutic decision-making process of whether to start immunomodulatory medications.