National burden of the pharmaceutical cost of wet compresses and its cost predictors: nationwide cross-sectional study in Japan
National burden of the pharmaceutical cost of wet compresses and its cost predictors: nationwide cross-sectional study in Japan
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DOI：
10.1186/s13561-019-0238-6
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发表时间：
2019-06-29
影响因子：
2.4
通讯作者：
Yokoyama, Kazuhito
中科院分区：
文献类型：
--
作者：
Itoh, Hiroaki;Saito, Tomoyuki;Yokoyama, Kazuhito
背景资料：虽然在日本的医疗机构中每天都有大量的湿敷处方，但我们对湿敷费用的国家负担及其处方细节的了解还远远不够。我们调查了日本每年处方湿敷的药品费用的国家负担，并使用全国范围的健康保险索赔数据估计了该费用的预测因素。方法：我们从第二版“NDB Open Data Japan”网站获得的汇总表文件中提取了有关湿敷产品的记录，并按患者的5岁年龄组、性别、和省。此外，还以都道府县为单位进行了生态学研究，并以每位居民的年龄标准化湿敷费用为因变量进行了多元线性回归分析。结果：2015年度，日本每年的湿敷药品费用为1490亿日元（11.8亿欧元，13.3亿美元）。多元线性回归分析显示，每10万居民拥有骨科医师和康复医师的人数与每名居民每年的湿敷药品费用呈显著正相关（分别为P = 0.042和P = 0.008）。在日本，每年处方的湿敷药物费用对国家有限的医疗资源有相当大的影响。每100，000名居民中的骨科医生和康复医生数量可能是日本湿敷成本的独立预测因素。
Background: Although a high number of wet compresses are prescribed daily in medical institutions in Japan, our understanding of the national burden of the cost of wet compresses and the details regarding their prescription is far from complete. We investigated the national burden of the annual pharmaceutical cost of wet compresses prescribed in Japan and estimated the predictors of this cost using nationwide health insurance claims data.Methods: We extracted the records on wet compress products from summary table files obtained from the second version of the "NDB Open Data Japan" website and calculated the annual pharmaceutical cost of wet compresses by patients' 5-year age group, sex, and prefecture. We also conducted an ecological study treating each prefecture as an individual unit and multiple linear regression analyses using the age-standardized cost of wet compresses per resident as a dependent variable.Results: The annual pharmaceutical cost of wet compresses prescribed in Japan in fiscal year 2015 was 149.0 billion Japanese yen (1.18 billion euros; 1.33 billion USD). Multiple linear regression analyses showed that the number of orthopedists and rehabilitation physicians per 100,000 residents were significantly positively associated with the annual pharmaceutical cost of wet compresses per resident (P = 0.042 and P = 0.008, respectively).Conclusions: The annual pharmaceutical cost of wet compresses prescribed in Japan has a considerable impact on the nation's limited healthcare resources. The number of orthopedists and rehabilitation physicians per 100,000 residents may be independent predictors of the wet compress cost in Japan.