Intramuscular metabolism during low-intensity resistance exercise with blood flow restriction
Intramuscular metabolism during low-intensity resistance exercise with blood flow restriction
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DOI：
10.1152/japplphysiol.90368.2008
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发表时间：
2009-04-01
影响因子：
3.3
通讯作者：
Tsutsui, Hiroyuki
中科院分区：
文献类型：
--
作者：
Suga, Tadashi;Okita, Koichi;Tsutsui, Hiroyuki
Suga T，Okita K，Morita N，Yokota T，Hirabayashi K，Horiuchi M，Takada S，Takahashi T，Omokawa M，Kinukawa S，Ttsutsui H。血流限制的低强度阻力运动期间的肌内代谢。 J Appl Physiol 106: 1119-1124, 2009。首次发表于 2009 年 2 月 12 日； doi:10.1152/japplphyol.90368.2008.-尽管最近的研究报道，限制血流的低强度阻力训练可以有效地对肌肉施加压力，并提供与高强度阻力训练相当的快速肌肉肥大和力量增益，但其确切机制及其普遍性尚未阐明。我们研究了血流限制的低强度阻力运动期间的肌内代谢，并使用 P-31 磁共振波谱将其与无血流限制的高强度和低强度阻力运动进行比较。 26 名健康受试者（22 +/- 4 岁）参与并进行单侧跖屈（30 次/分钟）2 分钟。方案如下：低强度运动（L）使用一次重复最大负荷（1 RM）的20%，L加上血流限制（LR），以及使用65% 1 RM（H）的高强度运动。获得静息和运动期间的肌内磷酸肌酸 (PCr) 和二质子化磷酸盐 (H2PO4-) 水平以及肌内 pH 值。我们发现 LR 期间 PCr 消耗、H2PO4- 增加和肌内 pH 值下降均显着大于 L 期间（P < 0.001）；然而，LR 中的那些显着低于 H 中的那些（P < 0.001）。通过无机磷酸盐分裂评估的快肌纤维募集发生在 LR 组中，只有 31% 的受试者发生，而 H 组中则为 70%。 总之，通过血流限制，低强度抗阻运动期间骨骼肌的代谢应激显着增加，但一般没有达到高强度抗阻运动期间的水平。这种新的阻力训练方法需要进行检查以优化方案，以达到与高强度阻力训练的等效性。
Suga T, Okita K, Morita N, Yokota T, Hirabayashi K, Horiuchi M, Takada S, Takahashi T, Omokawa M, Kinugawa S, Tsutsui H. Intramuscular metabolism during low-intensity resistance exercise with blood flow restriction. J Appl Physiol 106: 1119-1124, 2009. First published February 12, 2009; doi:10.1152/japplphysiol.90368.2008.-Although recent studies have reported that low-intensity resistance training with blood flow restriction could stress the muscle effectively and provide rapid muscle hypertrophy and strength gain equivalent to those of high-intensity resistance training, the exact mechanism and its generality have not yet been clarified. We investigated the intramuscular metabolism during low-intensity resistance exercise with blood flow restriction and compared it with that of high-intensity and low-intensity resistance exercises without blood flow restriction using P-31-magnetic resonance spectroscopy. Twenty-six healthy subjects (22 +/- 4 yr) participated and performed unilateral plantar flexion (30 repetitions/min) for 2 min. Protocols were as follows: low-intensity exercise (L) using a load of 20% of one-repetition maximum (1 RM), L with blood flow restriction (LR), and high-intensity exercise using 65% 1 RM (H). Intramuscular phosphocreatine (PCr) and diprotonated phosphate (H2PO4-) levels and intramuscular pH at rest and during exercise were obtained. We found that the PCr depletion, the H2PO4- increase, and the intramuscular pH decrease during LR were significantly greater than those in L (P < 0.001); however, those in LR were significantly lower than those in H (P < 0.001). The recruitment of fast-twitch fiber evaluated by inorganic phosphate splitting occurred in only 31% of the subjects in LR, compared with 70% in H. In conclusion, the metabolic stress in skeletal muscle during low-intensity resistance exercise was significantly increased by applying blood flow restriction, but did not generally reach that during high-intensity resistance exercise. This new method of resistance training needs to be examined for optimization of the protocol to reach equivalence with high-intensity resistance training.