Exponential distribution of locomotion activity in cell cultures
Exponential distribution of locomotion activity in cell cultures
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DOI：
10.1103/physrevlett.81.3038
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发表时间：
1998-10-05
影响因子：
8.6
通讯作者：
Vicsek, T
中科院分区：
文献类型：
--
作者：
Czirok, A;Schlett, K;Vicsek, T
用计算机控制的视频显微镜测量了几种细胞类型的体外速度，可以记录细胞在几天内的运动轨迹。基于我们的大型数据集，我们表明运动活动表现出普遍的指数分布。因此，由复杂的细胞过程引起的运动可以用一个意想不到但非常简单的分布函数来很好地描述。一个简单的现象学模型基于各种细胞过程的相互作用和有限的ATP生产速率被提出来解释这些实验结果。
In vitro velocities of several cell types have been measured using computer controlled video microscopy, which allowed the recording of the cells' trajectories over several days. On the basis of our large data sets we show that the locomotion activity displays a universal exponential distribution. Thus, motion resulting from complex cellular processes can be well described by an unexpected, but very simple, distribution function. A simple phenomenological model based on the interaction of various cellular processes and finite ATP production rate is proposed to explain these experimental results.