Adverse pregnancy and perinatal outcomes in Latin America and the Caribbean: systematic review and meta-analysis.
Adverse pregnancy and perinatal outcomes in Latin America and the Caribbean: systematic review and meta-analysis.
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DOI：
10.26633/rpsp.2022.21
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发表时间：
2022
期刊：
影响因子：
--
通讯作者：
Quinteros ME
中科院分区：
文献类型：
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作者：
Blanco E;Marin M;Nuñez L;Retamal E;Ossa X;Woolley KE;Oludotun T;Bartington SE;Delgado-Saborit JM;Harrison RM;Ruiz-Rudolph P;Quinteros ME
评估拉丁美洲和加勒比地区妊娠高血压综合征、先兆子痫、妊娠期糖尿病、低出生体重和早产的现患率和可能范围，并评估估计的异质性。我们对2000年至2019年以英语、西班牙语或葡萄牙语发表的拉丁美洲和加勒比地区人口中孕产妇和围产期不良结局的流行率的观察性研究进行了系统的综述和荟萃分析。我们搜索了PubMed、Embase和丁香。我们通过研究设计和偏倚水平估计了时点患病率，并评估了总体的异质性和在亚组分析中的异质性。在检索到的1087条记录中，有50篇文章被纳入综述：2篇关于妊娠高血压疾病，14篇关于先兆子痫，6篇关于妊娠期糖尿病，9篇关于低出生体重，19篇关于早产。由于研究数量较少，不能对妊娠期高血压疾病进行荟萃分析。先兆子痫、妊娠期糖尿病、低出生体重和早产的患病率估计值和95%可信区间分别为6.6%(95%CI：4.9%，8.6%)、8.5%(95%CI：3.9%，14.7%)、8.5%(95%CI：7.2%，9.8%)和10.0%(95%CI：8.0%，12.0%)。通过研究设计，我们观察到总体上和研究设计上的显著异质性。没有观察到偏差水平在估计上的主要差异。这项研究的结果提供了对拉丁美洲和加勒比地区一些最普遍的不良妊娠和围产期结局的最新估计。他们强调，流行率估计中存在重要的异质性，这可能反映该地区人口的多样性。
To estimate the point prevalence and likely ranges of pregnancy-induced hypertension, pre-eclampsia, gestational diabetes, low birth weight and preterm delivery in Latin America and the Caribbean, and evaluate the heterogeneity of the estimates. We conducted a systematic review and meta-analysis of observational studies reporting the prevalence of maternal and perinatal adverse outcomes in populations in Latin American and the Caribbean published between 2000 and 2019 in English, Spanish, or Portuguese. We searched PubMed, Embase, and LILACS. We estimated the point prevalence and evaluated overall heterogeneity and, in sub-group analyses, heterogeneity by study design and level of bias. Of 1087 records retrieved, 50 articles were included in the review: two on hypertensive disorders of pregnancy, 14 on pre-eclampsia, six on gestational diabetes, nine on low birth weight and 19 on preterm birth. No meta-analysis for hypertensive disorders of pregnancy could be done because of the small number of studies. Point prevalence estimates and 95% confidence intervals (CIs) for pre-eclampsia, gestational diabetes, low birth weight, and preterm birth were: 6.6% (95% CI: 4.9%, 8.6%), 8.5% (95% CI: 3.9%, 14.7%), 8.5% (95% CI: 7.2%, 9.8%), and 10.0% (95% CI: 8.0%, 12.0%), respectively. We observed substantial heterogeneity overall and by study design. No major differences in estimates were observed by level of bias. The results of this study provide updated estimates of some of the most prevalent adverse pregnancy and perinatal outcomes in Latin America and the Caribbean. They highlight that important heterogeneity exists in prevalence estimates, which may reflect the diversity of populations in the region.
影响因子：
4.5
作者：
Rodríguez López S;Tumas N;Ortigoza A;de Lima Friche AA;Diez-Roux AV
通讯作者：
Diez-Roux AV