Environmental factors in schizophrenia: The role of migrant studies

Environmental factors in schizophrenia: The role of migrant studies
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DOI:
10.1093/schbul.sbj076
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发表时间:
2006-07-01
影响因子:
6.6
通讯作者:
Morgan, Craig
Morgan, Craig
中科院分区:
医学1区
文献类型:
--
作者:
Fearon, Paul;Morgan, Craig

文献摘要

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现在有令人信服的证据表明,一些国家的移民群体患精神分裂症和其他精神病的风险较高。虽然早期研究的结果受到质疑,并被一些人归因于方法上的缺陷和诊断偏差,但最近来自不同国家的更严格的研究仍然发现发病率显着增加。虽然这一现象本身就是一个重要的健康问题,但了解发病率上升的原因可能会对精神分裂症和其他精神障碍的病因提供有价值的见解。下一阶段研究的挑战是确定相关的风险因素,以及它们如何相互作用,增加移民群体和普通人群中精神病的风险。
There is now compelling evidence that migrant groups in several countries have an elevated risk of developing schizophrenia and other psychotic disorders. Though the findings of earlier studies were greeted with skepticism, and ascribed by some to have methodological shortcomings and diagnostic biases, the more rigorous recent studies, from a variety of countries, have still found markedly increased incidence rates. While this phenomenon is an important health issue in its own right, understanding the reasons for the increased rates may provide valuable insights into the causes of schizophrenia and other psychotic disorders in general. The challenge for the next phase of studies is to identify the relevant risk factors and how they might interact to increase the risk of psychosis, both in migrant groups and in the general population.