[Trend analysis of cancer mortality in China between 1989 and 2008].
[Trend analysis of cancer mortality in China between 1989 and 2008].
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DOI：
10.3760/cma.j.issn.0253-3766.2012.07.011
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发表时间：
2012-07-01
期刊：
影响因子：
--
通讯作者：
Chen, Wan-qing
中科院分区：
文献类型：
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作者：
Zeng, Hong-mei;Zheng, Rong-shou;Chen, Wan-qing
目的：癌症是中国主要的死亡原因之一。该研究旨在研究1989-2008年中国城乡地区癌症死亡率的时间趋势。方法：对1989 ~ 2008年全国癌症登记数据库中所有癌症的死亡率数据进行整理和核对。年龄标准化死亡率采用直接法计算，采用1982年中国人口和世界Segi人口。采用联合点回归获得死亡率的年百分比变化（APC）。计算并分析前10位的肿瘤部位。死亡率与美国的统计数据进行了比较。结果：1989 - 2008年，粗癌死亡率呈上升趋势，年变化率（APC）为1.0%。年龄标准化后，死亡率明显下降，APC为-1.2%。在城市地区，肺癌是最常见的死亡癌症，而在农村地区，胃癌和食道癌仍然是最常见的死亡癌症。特别是，在城市和农村地区，肺癌的死亡率都在上升。胃癌和食管癌的死亡率在城市地区有所下降。与美国的癌症死亡率相比，中国男性的癌症死亡率仍然最高。中国女性癌症死亡率的下降趋势不如美国明显。结论：1989 - 2008年间，中国癌症粗死亡率呈上升趋势，而年龄标准化死亡率呈下降趋势。在中国，癌症仍然是威胁人们生命的重大公共卫生问题。未来需要有效的干预措施来控制和预防癌症。
OBJECTIVE: Cancer is one of the leading causes of death in China. The study aimed to examine the temporal trend of cancer mortality rate during 1989-2008 in urban and rural areas of China.METHODS: The mortality data of all cancers from 1989 to 2008 from National Cancer Registry database were sorted and checked. Age standardized mortality rates were calculated by the direct methods using the China population of 1982 and World Segi's population. Joinpoint regression was performed to obtain the annual percentage changes (APC) in mortality rates. The top ten cancer sites were calculated and analyzed. The mortality rates were compared with statistics of the United States.RESULTS: From 1989 to 2008, the trend of crude cancer mortality increased with an annual percentage change (APC) of 1.0%. After age standardization, the mortality rate was significantly decreased, with an APC of -1.2%. In urban areas, lung cancer was the most common cancer of death, whereas in rural areas, stomach cancer and esophageal cancer remained top cancers of death. Especially, in both urban and rural areas, the mortality of lung cancer was on increase. The mortality rates of stomach and esophageal cancers showed a decrease in urban areas. Compared with the cancer mortality rates of the United States, the Chinese cancer mortality rate in males remained highest. The decreasing trend of cancer mortality in females of China was less obvious than that of the United States.CONCLUSIONS: The crude mortality rates of cancer in China show an increase whereas the age standardized mortality raters has declined between 1989 and 2008. Cancer is still a major public health issue threatening people's life in China. Effective intervention for cancer control and prevention is needed in the future.