Squirming with a backward-propelling cage

Squirming with a backward-propelling cage
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DOI:
10.1063/5.0152711
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发表时间:
2023-05
期刊:
影响因子:
4.6
通讯作者:
J. Della-Giustina;H. Nganguia;E. Demir
J. Della-Giustina;H. Nganguia;E. Demir
中科院分区:
工程技术2区
文献类型:
--
作者:
J. Della-Giustina;H. Nganguia;E. Demir

文献摘要

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包裹在液滴中的蠕动装置代表了某些药物输送系统的最小模型。在牛顿流体中用球形笼子游泳的球形蠕动物体[Reigh等人,“用笼子游泳:液滴内的低雷诺数运动”,Soft Matter 13,3161(2017)],发现蠕动物体和液滴总是朝同一方向推进,尽管速度不同。我们将模型扩展到包括颗粒形状和介质的异质性,这是两个生物学上相关的特征。我们的结果揭示了一种新的行为:在高度不均匀的介质中,由球形蠕动和球形液滴组成的构型产生了液滴的反向运动。
A squirmer enclosed in a droplet represents a minimal model for some drug delivery systems. In the case of a spherical squirmer swimming with a spherical cage in a Newtonian fluid [Reigh et al., “Swimming with a cage: Low-Reynolds-number locomotion inside a droplet,” Soft Matter 13, 3161 (2017)], it was found that the squirmer and droplet always propelled in the same direction albeit at different speeds. We expand the model to include particles' shape and medium's heterogeneity, two biologically relevant features. Our results reveal a novel behavior: a configuration that consists of a spherical squirmer and a spheroidal droplet in highly heterogeneous media yields a backward motion of the droplet.