PROGRESS IN THE TREATMENT OF HODGKINS-DISEASE IN THE UNITED-STATES, 1973 VERSUS 1983 - THE PATTERNS OF CARE STUDY

PROGRESS IN THE TREATMENT OF HODGKINS-DISEASE IN THE UNITED-STATES, 1973 VERSUS 1983 - THE PATTERNS OF CARE STUDY
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DOI:
10.1002/1097-0142(19941215)74:12
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发表时间:
1994-12-15
期刊:
影响因子:
6.2
通讯作者:
OWEN, JB
OWEN, JB
中科院分区:
医学1区
文献类型:
--
作者:
HOPPE, RT;HANLON, AL;OWEN, JB

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背景自20世纪60年代初以来,霍奇金病患者的预后已显着改善。这种改善的原因是多方面的。在美国放射学会的护理模式研究中,完成了1973年和1983年对霍奇金病患者治疗过程和结果的全国调查。我们比较了I-II期霍奇金病患者和单纯放疗患者的数据。两个不同治疗时期患者的临床特征相似。治疗参数存在重要差异。与1973年相比,1983年更普遍地使用专用模拟器、常规端口电影的性能、使用线性加速器、使用单独成形的块以及对扩展字段的治疗。在1983年的研究中,治疗野的精确性也被判定为上级。与1973年相比,1983年接受治疗的患者的生存率和无复发生存率有所提高。放射治疗技术的改进与霍奇金病患者治疗结果的改善相关。从1973年到1983年,国家标准有所提高。
Background. The prognosis for Hodgkin's disease patients has improved significantly since the early 1960s. The reasons for this improvement are multifactorial.Methods. In the Patterns of Care Study of the American College of Radiology, national surveys to examine process and outcome of patients treated for Hodgkin's disease in 1973 and 1983 were completed. Data were compared for patients who had Stage I-II Hodgkin's disease and who were treated with radiation therapy alone.Results. Clinical characteristics of the patients in the two different treatment eras were similar. There were important differences in treatment parameters. In 1983 compared with 1973, there was more common use of a dedicated simulator, performance of routine port films, use of linear accelerators, use of individually shaped blocks, and treatment to extended fields. Adequacy of treatment fields also was judged superior in the 1983 study. There were improvements in survival and relapse-free survival for patients treated in 1983 versus 1973.Conclusions. Improvement in radiation therapy technique is associated with an improved outcome for patients treated for Hodgkin's disease. The national standards have improved during the time from 1973 to 1983.