TGFβ1-Smad Signaling Pathway Participates in Interleukin-33 Induced Epithelial-to-Mesenchymal Transition of A549 Cells

TGFβ1-Smad Signaling Pathway Participates in Interleukin-33 Induced Epithelial-to-Mesenchymal Transition of A549 Cells
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TGFβ1-Smad 信号通路参与 Interleukin-33 诱导的 A549 细胞上皮间质转化

DOI:
10.1159/000494241
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发表时间:
2018-10
影响因子:
--
通讯作者:
Zhen Shun Cheng
Zhen Shun Cheng
中科院分区:
医学1区
文献类型:
--
作者:
Qiu Yue Tan;Zhen Shun Cheng

文献摘要

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背景/目的:上皮间质转化(EMT)已被证实参与肺纤维化的发生和发展。本研究旨在探讨转化生长因子β1(TGFβ1)-smad信号通路在人肝癌细胞凋亡中的作用。
Backgrounds/Aims: Epithelial-to-mesenchymal transition (EMT) has been proven to be involved in development and progression of pulmonary fibrosis. This study aims to investigate the role of transforming growth factor β1 (TGFβ1)-smad signaling pathway in th