The X-trials: Neural correlates of an inhibitory control task in children and adults

The X-trials: Neural correlates of an inhibitory control task in children and adults
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DOI:
10.1162/089892903321593144
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发表时间:
2003-04-01
影响因子:
3.2
通讯作者:
Nelson, CA
Nelson, CA
中科院分区:
医学3区
文献类型:
--
作者:
Davis, EP;Bruce, J;Nelson, CA

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本研究采用事件相关电位(ERP)技术,考察了6岁儿童和成年儿童在抑制控制任务中神经加工的发育差异。20名成年人和21名儿童完成了一项任务,要求他们选择性地对tal-get刺激做出反应,同时抑制对同样突出的非目标刺激的反应。因为这个任务之前已经使用功能性磁共振成像(fMRI)进行了研究,所以非正式地检查了fMRI和ERP结果之间的关系。结果表明,P3的潜伏期和波幅的不同类型的试验区分。然而,成人和儿童的事件相关神经活动模式不同。这些结果表明,成人和儿童可能使用不同的过程来执行这项任务,对解释以前的fMRI结果有影响。
Event-related potentials (ERPs) were used to examine developmental differences between adults and 6-year-old children in the neural processes involved in an inhibitory control task. Twenty adults and 21 children completed a task that required them to selectively respond to tal-get stimuli while inhibiting responses to equally, salient non-target stimuli. Because this task had been previously studied using functional magnetic resonance imaging (fMRI) the relation between the fMRI and ERP findings was informally examined. The results indicate that latency and amplitude of the P3 differentiated the different types of trials. However, the pattern of event-related neural activity differed for adults and children. These results, which suggest that adults and children may he using different processes to perform this task, have implications for the interpretation of the previous fMRI findings.