Diffusion coefficients of phenylbutazone in supercritical CO2 and in ethanol
Diffusion coefficients of phenylbutazone in supercritical CO2 and in ethanol
复制标题
保泰松在超临界 CO2 和乙醇中的扩散系数
DOI：
10.1016/j.chroma.2013.01.019
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发表时间：
2013
影响因子：
4.1
通讯作者：
Chang Yi Kong
中科院分区：
文献类型：
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作者：
安江智広;須藤雅夫;出本公平,坂部淳一,内田博久,伊藤眞義,杉本宣裕;Chang Yi Kong
采用色谱脉冲响应（CIR）法测定了保泰松在超临界CO2中无限稀释时的扩散系数D12。测量在308.2至343.2 K的温度范围内进行，压力高达40.0 MPa。此外，还用泰勒色散法测定了298.2- 333.2K和常压下保泰松在乙醇中无限稀释时的D_（12）数据。保泰松的D12值从298.2 K和0.1 MPa乙醇中的4.45 × 10− 10 m2 s − 1增加到343.2 K和14.0 MPa超临界CO2中的1.43 × 10− 8 m2 s − 1。结果表明，保泰松在超临界CO_2和乙醇中的扩散数据在从超临界状态到液态的较宽粘度范围内均能用流体动力学方程满意地表示，112个数据点的平均绝对相对偏差为5.4%。
The diffusion coefficientsD12of phenylbutazone at infinite dilution in supercritical CO2were measured by the chromatographic impulse response (CIR) method. The measurements were carried out over the temperature range from 308.2 to 343.2 K at pressures up to 40.0 MPa. In addition, theD12data of phenylbutazone at infinite dilution in ethanol were also measured by the Taylor dispersion method at 298.2–333.2 K and at atmospheric pressure. TheD12value of phenylbutazone increased from 4.45 × 10−10m2s−1at 298.2 K and 0.1 MPa in ethanol to about 1.43 × 10−8m2s−1at 343.2 K and 14.0 MPa in supercritical CO2. It was found that all diffusion data of phenylbutazone measured in this study in supercritical CO2and in ethanol can be satisfactorily represented by the hydrodynamic equation over a wide range of fluid viscosity from supercritical state to liquid state with average absolute relative deviation of 5.4% for 112 data points.