Diagnostic value of terminal ileum biopsies in patients with abnormal terminal ileum mucosal appearance
Diagnostic value of terminal ileum biopsies in patients with abnormal terminal ileum mucosal appearance
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DOI：
10.5152/ucd.2015.2756
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发表时间：
2015-09-01
影响因子：
0.6
通讯作者：
Zengin, A. Kagan
中科院分区：
文献类型：
--
作者：
Velidedeoglu, Mehmet;Arikan, A. Enes;Zengin, A. Kagan
目的：探讨不考虑炎症性肠病的回肠末端黏膜形态异常患者在结肠镜检查中常规活检的必要性。材料与方法：对2008年1月至2009年2月在某民营医院接受结肠镜检查的57例回肠末端插管患者进行回顾性分析。结果：男33例，女24例，平均年龄44.12±11.42岁。22例患者异常表现为溃疡和/或糜烂。10例有粘膜结节，24例有红斑。S从盲肠到回肠的时间为28.78±24.30，回肠平均长度为12.93±6.05 cm。根据回肠覆盖距离分组间的诊断效率无差异，但超过2 cm是重要的。结论：在不考虑炎症性肠病的情况下，回肠末端黏膜形态异常的患者不需要进行常规活检。在这些患者中，组织病理学也显示非特异性回肠炎。此外，在这些患者中，肉眼病理诊断与组织病理学诊断重叠，诊断率低，临床意义不大。
Objective: To investigate the necessity of obtaining routine ileal biopsy during colonoscopy in the patients with abnormal terminal ileum mucosal appearance if the inflammatory bowel disease is not considered.Material and Methods: A retrospective analysis was performed for 57 patients who were referred to a private hospital for colonoscopy between January 2008 and February 2009, in whom terminal ileum intubation was achieved and an abnormal appearance was observed.Results: There were 33 men and 24 women; the mean age was 44.12 +/- 11.42 years. In 22 patients, the abnormality was ulcers and/or erosions. In 10 patients, there were mucosal nodularity and in 24, the finding was erythema. The time to reach to ileum from cecum was 28.78 +/- 24.30 s. The mean length of the examined ileum was 12.93 +/- 6.05 cm. There was no difference between groups according to distance covered in the ileum for diagnostic yield, but going further than 2 cm was important.Conclusion: There should be no need to obtain routine biopsy in patients with abnormal terminal ileum mucosa appearance, when inflammatory bowel disease is not considered. In these patients, histopathology also reveals nonspecific ileitis. Furthermore, in these patients, the macroscopic pathological diagnosis overlaps the histopathology, and it has a low diagnostic yield and lower clinical significance.