Sleep Problems in Children with Fetal Alcohol Spectrum Disorders
Sleep Problems in Children with Fetal Alcohol Spectrum Disorders
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DOI：
10.5664/jcsm.2038
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发表时间：
2012-01-01
影响因子：
4.3
通讯作者：
Owens, Judith
中科院分区：
文献类型：
--
作者：
Chen, Maida Lynn;Olson, Heather Carmichael;Owens, Judith
研究目的：据报道，患有胎儿酒精谱系障碍（FASD）的儿童的睡眠问题很常见，但尚未得到很好的表征。目标是：（1）使用儿童睡眠习惯问卷（CSHQ）评估FASD儿童的睡眠问题;（2）将CSHQ结果与先前报道的社区样本进行比较;（3）描述FASD儿童的多导睡眠图结果。CSHQ结果与以前发表的类似年龄的社区样本的原始数据进行了比较。参与者与FASD和升高的CSHQ分数提供过夜polysomnography.Results：33名儿童FASD（4.1-12.1岁）入组; 85%的儿童FASD得分高于临床截止总分41分，反映了显着的睡眠障碍。子域分数升高主要发生在与小儿失眠有关的领域。共病ADHD患者在其他子领域的CSHQ升高，总分无差异。与社区样本相比，FASD儿童的CSHQ总分较高（52 vs. 39，p < 0.001）。多导睡眠图，在5个科目完成，发现轻度睡眠呼吸障碍和碎片睡眠升高非呼吸唤醒indics.Conclusions：临床上显着的睡眠问题是存在于儿童与FASD的主观和客观的措施。需要进一步的研究来更好地描述这些睡眠障碍及其对该临床人群整体健康和日间神经行为问题的影响。
Study Objectives: Sleep problems in children with fetal alcohol spectrum disorders (FASD) are reportedly common but not well characterized. Objectives were to: (1) assess sleep concerns in children with FASD using a caregiver-report survey, the Children's Sleep Habits Questionnaire (CSHQ); (2) compare CSHQ results with those of previously reported community sample; and (3) describe pilot polysomnography findings in children with FASD.Methods: Children with FASD were recruited from a behavioral intervention study, and participating caregivers completed the CSHQ. CSHQ results were compared with the original data from a previously published community sample of similar age. Participants with FASD and elevated CSHQ scores were offered overnight polysomnography.Results: Thirty-three children with FASD (4.1-12.1 years) were enrolled; 85% of children with FASD scored above the clinical cutoff Total Score of 41, reflecting marked sleep disturbance. Elevated subdomain scores occurred primarily in areas concerning for pediatric insomnia. Those with comorbid ADHD had elevated CSHQ on additional subdomains with no difference in Total Scores. Compared with the community sample, children with FASD had higher Total Scores on the CSHQ (52 vs. 39, p < 0.001). Polysomnography, completed in 5 subjects, revealed mild sleep disordered breathing and fragmented sleep with elevated non-respiratory arousal indices.Conclusions: Clinically significant sleep problems are present in children with FASD on both subjective and objective measures. Further investigation is needed to better describe these sleep disturbances and their impact on overall health and daytime neurobehavioral problems in this clinical population.