Immobilization hypercalcemia after single limb fractures in children and adolescents.

Immobilization hypercalcemia after single limb fractures in children and adolescents.
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儿童和青少年单肢骨折后制动高钙血症。

DOI:
10.1001/archpedi.1978.02120310024004
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发表时间:
1978
期刊:
影响因子:
26.1
通讯作者:
L. Finberg
L. Finberg
中科院分区:
医学1区
文献类型:
--
作者:
J. F. Rosen;D. Wolin;L. Finberg

文献摘要

被引文献

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·在儿童年龄组中,单肢骨折后的固定性高钙血症在儿童年龄组中很少报道。然而,在这两年的研究期间,在12名患者中,有6名患者发生了固定性高钙血症,与单肢承重骨骨折后尿钙/肌酐比值和血清离子钙水平的升高有关。我们认为,儿童和青少年单侧负重骨骨折后易发生固定性高钙血症,床上运动不能预防固定性高钙血症,连续监测血清离子钙和尿钙/肌酐比值是治疗此类患者的关键措施,尽管完全松动是治愈的,但短暂降钙素治疗在逆转钙代谢紊乱方面是非常有效的。(Am J Dis Child132:560-564,1978)
• Immobilization hypercalcemia following a single limb fracture of one weight bearing bone has been reported rarely in the pediatric age group. Nevertheless, in six of 12 patients immobilization hypercalcemia developed, associated with elevations in the urinary calcium/creatinine ratio and serum levels of ionized calcium after a single limb fracture of a weight-bearing bone during this two-year study period. We suggest that immobilization hypercalcemia occurs frequently in both children and adolescents after a single limb fracture of one weight-bearing bone, exercises in bed fail to prevent immobilization hypercalcemia, serial measurements of the serum ionized calcium and the urinary calcium/creatinine ratio are critical measures in treating such patients, and though complete mobilization is curative, transient calcitonin therapy is highly effective in reversing the disorders in calcium metabolism. (Am J Dis Child132:560-564, 1978)