Effect of Depression on Self-Management Behaviors and Health Outcomes in Adults with Type 2 Diabetes
Effect of Depression on Self-Management Behaviors and Health Outcomes in Adults with Type 2 Diabetes
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DOI：
10.2174/157339905774574356
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发表时间：
2005-01-01
影响因子：
3.3
通讯作者：
Egede, Leonard E.
中科院分区：
文献类型：
--
作者：
Egede, Leonard E.
糖尿病是一种非常普遍的慢性和衰弱的疾病，与显著的发病率、死亡率和增加的医疗费用有关。抑郁症也非常普遍，是导致残疾、工作场所缺勤、生产力下降和卫生保健资源使用增加的主要原因。有证据表明，糖尿病患者患抑郁症的可能性是非糖尿病患者的两倍，而且大约30%的糖尿病患者有临床相关的抑郁症。合并抑郁症与糖尿病患者的不良健康后果密切相关，包括血糖控制不佳，并发症风险增加，对药物的依从性降低，对饮食建议的依从性降低，以及医疗费用增加。本文综述了抑郁症的流行病学，抑郁症对糖尿病患者自我管理行为和糖尿病特有结果的影响，这些影响的潜在途径(介质和调节因子)，以及有效的治疗策略。
Diabetes is a highly prevalent chronic and debilitating condition that is associated with significant morbidity, mortality, and increased health care costs. Depression is also highly prevalent and is a leading cause of disability, work place absenteeism, lost productivity, and increased use of health care resources. There is evidence that persons with diabetes are twice as likely to have depression as persons without diabetes and that similar to 30% of persons with diabetes have clinically relevant depression.Comorbid depression is strongly associated with adverse health outcomes in persons with diabetes including poor glycemic control, increased risk of complications, decreased adherence to medications, decreased adherence to dietary recommendations, and increased health care costs.This article reviews the epidemiology of depression, the effect of depression on diabetes self-management behavior and diabetes-specific outcomes, potential pathways (mediators and moderators) for these effects, and effective treatment strategies for depression in individuals with type 2 diabetes.