Rapid inactivation of human respiratory RNA viruses by deep ultraviolet irradiation from light-emitting diodes on a high-temperature- annealed AlN/Sapphire template
Rapid inactivation of human respiratory RNA viruses by deep ultraviolet irradiation from light-emitting diodes on a high-temperature- annealed AlN/Sapphire template
复制标题
DOI：
10.29026/oea.2023.230004
复制
发表时间：
2023-01-01
影响因子：
14.1
通讯作者：
Xu, Ke
中科院分区：
文献类型：
--
作者：
Jiang, Ke;Liang, Simeng;Xu, Ke
在公共环境和便携式使用中，追求空气传播的人类呼吸道RNA病毒的高效环保消毒。藻类基深紫外（DUV）发光二极管（LED）具有波长可变、快速杀菌、环保、小型化等优点，具有很高的应用潜力。因此，发射波长是否对消毒有影响，以及该装置在便携式条件下是否可行对各种呼吸道RNA病毒进行消毒至关重要。本文在高温退火（HTA） AlN/Sapphire模板上制备了不同波长的algan基DUV led，并研究了其对几种呼吸道RNA病毒的灭活效果。在模板和上部n-AlGaN之间采用AlN/AlGaN超晶格来释放强压应力（SCS），提高了晶体质量和界面粗糙度。实现了波长为256、265和278 nm的DUV led，对应的光输出功率分别为6.8、9.6和12.5 mW，其中256 nm的led对SARS-CoV-2、甲型流感病毒（IAV）和人类副流感病毒（HPIV）等人类呼吸道RNA病毒的灭活效果最好，光功率密度（LPD）接近0.8 mW/cm(2)，灭活时间为10 s。这些结果将有助于先进的DUV LED在便携式和环保用途中高效广谱消毒病毒的应用。
Efficient and eco-friendly disinfection of air-borne human respiratory RNA viruses is pursued in both public environment and portable usage. The AlGaN-based deep ultraviolet (DUV) light-emission diode (LED) has high practical potentials because of its advantages of variable wavelength, rapid sterilization, environmental protection, and miniaturization. Therefore, whether the emission wavelength has effects on the disinfection as well as whether the device is feasible to sterilize various respiratory RNA viruses under portable conditions is crucial. Here, we fabricate AlGaN-based DUV LEDs with different wavelength on high-temperature-annealed (HTA) AlN/Sapphire templates and investigate the inactivation effects for several respiratory RNA viruses. The AlN/AlGaN superlattices are employed between the template and upper n-AlGaN to release the strong compressive stress (SCS), improving the crystal quality and interface roughness. DUV LEDs with the wavelength of 256, 265, and 278 nm, corresponding to the light output power of 6.8, 9.6, and 12.5 mW, are realized, among which the 256 nm-LED shows the most potent inactivation effect in human respiratory RNA viruses, including SARS-CoV-2, influenza A virus (IAV), and human parainfluenza virus (HPIV), at a similar light power density (LPD) of similar to 0.8 mW/cm(2) for 10 s. These results will contribute to the advanced DUV LED application of disinfecting viruses with high potency and broad spectrum in a portable and eco-friendly use.