Prolonged elevation of hypothalamic opioid peptide activity in women taking oral contraceptives.

Prolonged elevation of hypothalamic opioid peptide activity in women taking oral contraceptives.
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服用口服避孕药的女性下丘脑阿片肽活性长期升高。

DOI:
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发表时间:
1984
影响因子:
5.8
通讯作者:
M. Wilkinson
M. Wilkinson
中科院分区:
医学2区
文献类型:
--
作者:
R. Casper;R. Bhanot;M. Wilkinson

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To examine the hypothesis that endogenous opioid peptide activity is chronically elevated by oral contraceptives, we infused either naloxone or saline into 10 women during the use of, or 5-6 and 9-10 days after stopping, combination birth control pills. A paradoxical increase in prolactin occurred with naloxone infusion during and 5-6 days after stopping the pills. Serum LH levels were not significantly elevated by naloxone until 9-10 days after cessation of pill use. These results suggest that hypothalamic opioid peptide activity is continuously elevated in women taking oral contraceptives.
内源性阿片制剂调节人体脉动黄体生成激素的释放。
DOI: 10.1210/jcem-52-3-583
发表时间: 1981
期刊: The Journal of clinical endocrinology and metabolism
影响因子: --
作者:
Ropert,JF;Quigley,ME;Yen,SS
通讯作者: Yen,SS