Redox behavior of cytochrome oxidase in the rat brain measured by near-infrared spectroscopy
Redox behavior of cytochrome oxidase in the rat brain measured by near-infrared spectroscopy
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DOI：
10.1152/jappl.1997.83.6.1842
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发表时间：
1997-12-01
影响因子：
3.3
通讯作者：
Tamura, M
中科院分区：
文献类型：
--
作者：
Hoshi, Y;Hazeki, O;Tamura, M
利用近红外光谱，我们开发了一种新的方法来测量正常血液循环条件下的脑细胞色素氧化酶的氧化还原状态。我们的算法不需要细胞色素氧化酶的吸收系数，这与研究不同。我们采用这种方法来评价氧输送的变化对大鼠脑氧合的影响。当吸入氧分数以逐步的方式从100降低到
Using near-infrared spectroscopy,we developed a new approach for measuring the redox state of cytochrome oxidase in the brain under normal blood-circulation conditions. Our algorithm does not require the absorption coefficient of cytochrome oxidase, which differs from study to study. We employed this method for evaluation of effects of changes in oxygen delivery on cerebral oxygenation in rats. When fractional inspired oxygen was decreased in a stepwise manner from 100 to