The specific antibody to Brachyspira aalborgi in serum obtained from a patient with intestinal spirochetosis.

The specific antibody to Brachyspira aalborgi in serum obtained from a patient with intestinal spirochetosis.
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从肠螺旋体病患者的血清中获得的针对阿尔氏短螺旋体的特异性抗体。

DOI:
10.1292/jvms.68.1089
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发表时间:
2006
期刊:
The Journal of veterinary medical science
影响因子:
--
通讯作者:
Y. Adachi
Y. Adachi
中科院分区:
--
文献类型:
--
作者:
Y. Abe;Akiko Hirane;A. Yoshizawa;H. Nakajima;Y. Adachi

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用凝集试验对一例经组织病理学诊断为肠螺旋体病的患者血清进行了血清学诊断。人肠道螺旋体阿尔伯氏杆菌与人血清反应强烈,而对人具有潜在致病性的大肠杆菌与血清反应强烈,但其效价与其他3种不同。另一方面,从患者的活检样本中分离出肠道螺旋体(松本分离株)。分离株的形态、生化和遗传特征与阿尔氏贝氏菌非常相似。此外,松本分离菌株的蛋白质谱也与白僵杆菌相似,但与毛毛杆菌和水痢杆菌不同。松本分离菌的免疫印迹反应谱除74 kDa外与白僵杆菌的反应谱基本相似,但与毛毛杆菌和水痢杆菌的反应谱存在差异。因此,我们将松本分离株鉴定为阿尔伯氏杆菌,并诊断患者为阿尔伯氏杆菌感染。
Serum obtained from a patient histopathologically diagnosed as intestinal spirochetosis was investigated serodiagnostically by agglutination test. B. aalborgi which is a human intestinal spirochete reacted strongly with the human serum, while B. pilosicoli which has potential pathogenicity to humans reacted with the serum, but as strongly and its titer was different than the other three species. On the other hand, intestinal spirochetes (Matsumoto isolates) were isolated from the biopsy samples of the patient. The morphological, biochemical, and genetic characteristics of the isolates were very similar to those of B. aalborgi. Furthermore, the protein profiles of the Matsumoto isolates were also similar to those of B. aalborgi but were different than those of B. pilosicoli and B. hyodysenteriae. The reaction profiles of the Matsumoto isolates in immunoblotting were relatively similar to those of B. aalborgi except for a 74 kDa band but were different from those of B. pilosicoli and B. hyodysenteriae. Therefore, we identified the Matsumoto isolates as B. aalborgi and diagnosed the patient with a B. aalborgi infection.
从日本的两只小猎犬和一只杂种狗身上分离到短螺旋体。
DOI: --
发表时间: 2004
期刊: Journal of Veterinary Medical Science 66
影响因子: --
作者:
Manabe M.;et al.
通讯作者: et al.
首次从日本腹泻患者体内分离出的人类肠道螺旋体的形态特征。
DOI: --
发表时间: 2003
期刊: Microbiol Immunol 47
影响因子: --
作者:
Tasu C;Nakamura S. et al.
通讯作者: Nakamura S. et al.