Intercepting noncoding messages between germline and soma.
Intercepting noncoding messages between germline and soma.
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DOI：
10.1101/gad.199992.112
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发表时间：
2012-08
影响因子：
10.5
通讯作者：
Shan Gao;Yifan Liu
中科院分区：
文献类型：
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作者：
Shan Gao;Yifan Liu
越来越多的证据支持这样一种观点，即来自非编码rna （ncRNAs）的小rna是各种真核生物系统中表观遗传信息的移动载体。然而，在定义发送什么消息以及如何发送消息方面仍然存在挑战。在2012年8月1日出版的《基因与发育》杂志上，Schoeberl及其同事（pp. 1729-1742）详细分析了纤毛原生动物Tetrahymena有性繁殖过程中小rna的周转。结果揭示了小rna在形成种系和体细胞之间的交流中所起的令人惊讶的复杂作用。
There is growing evidence to support the notion that small RNAs derived from noncoding RNAs (ncRNAs) are mobile carriers of epigenetic information in diverse eukaryotic systems. However, challenges remain in defining what messages are being sent and how. In the August 1, 2012, issue of Genes & Development, Schoeberl and colleagues (pp. 1729-1742) reported a detailed analysis of the turnover of small RNAs during the sexual reproduction of the ciliated protozoan Tetrahymena. The results revealed surprisingly complicated roles played by small RNAs in shaping the communication between the germline and the soma.