Catatonic behavior, viral encephalopathy, and death. The problem of fatal catatonia.
Catatonic behavior, viral encephalopathy, and death. The problem of fatal catatonia.
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紧张性行为、病毒性脑病和死亡。
DOI：
10.1001/archpsyc.1972.01750300030005
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发表时间：
1972
影响因子：
--
通讯作者：
J. Sandt
中科院分区：
文献类型：
--
作者：
H. Penn;J. Racy;L. Lapham;M. Mandel;J. Sandt
致死性紧张症的病因多年来一直困扰着临床医生，其特征是以急性起病的躁动精神病为特征，常常以体温过高和死亡告终。争议集中在它与精神分裂症的关系上。本文报告了一例看似患有急性精神分裂症，后来出现紧张症特征的男子，尽管接受了电休克治疗和医疗支持，但他还是变得高热，并在9天后死亡。尸检显示，中枢神经系统出现了与病毒性脑炎一致的显微变化。我们认为，致命性紧张症有时可能是病毒作用于边缘区域的结果。精神症状和迅速恶化会给诊断和治疗带来困难。
The etiology of fatal catatonia, characterized by an agitated psychosis of acute onset which frequently ends in hyperthermia and death, has puzzled clinicians for many years. Controversy has centered around its relationship to schizophrenia. A case report is presented of a man who seemed to have acute schizophrenia, later developing catatonic features; he became hyperthermic and died after nine days despite electroconvulsive therapy and medical support. Postmortem examination revealed microscopic changes in the central nervous system consistent with viral encephalitis. We suggest fatal catatonia may on occasion be the result of a virus acting on the limbic area in particular. Psychiatric presentation and rapid deterioration would create difficulties in diagnosis and management.