Moderators of Treatment Effectiveness for War-Affected Youth With Depression in Northern Uganda
Moderators of Treatment Effectiveness for War-Affected Youth With Depression in Northern Uganda
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DOI：
10.1016/j.jadohealth.2012.02.010
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发表时间：
2012-12-01
影响因子：
7.6
通讯作者：
Bolton, Paul
中科院分区：
文献类型：
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作者：
Betancourt, Theresa S.;Newnham, Elizabeth A.;Bolton, Paul
目的：当我们建立受战争影响的青年抑郁症干预措施的证据基础时，了解调节治疗结果的因素至关重要。目前的研究调查如何性别和历史的绑架上帝抵抗军叛乱分子缓和治疗结果为战争影响youth.Methods：这项研究-一个三武装，随机，对照试验-进行了国内流离失所的战争影响的青少年在北方乌干达。有显著抑郁症状的参与者（N = 304; 57%女性; 14-17岁）被随机分配到人际心理治疗组（IPT-G），创造性游戏/娱乐组或等待列表控制条件。二次分析进行了数据从这个随机对照trial.Results：绑架的历史，由上帝抵抗军叛军的样本的42%。性别和绑架史相互作用，中度的IPT-G治疗抑郁症的有效性。在IPT-G干预组中，无外展病史的女性受试者的治疗有效性最高，效应量= 1.06。对于有外展病史的男性和女性受试者，IPT-G治疗抑郁症均有效（效应量分别为0.92和0.50）。男性受试者没有绑架的历史在IPT-G显示没有显着改善与那些在控制conditions.Conclusions：绑架的历史和性别是潜在的重要的调节剂的治疗效果，这表明这些因素需要考虑时，提供干预措施，为受战争影响的青年。IPT-G可能是一种有效的干预措施，女性受试者没有绑架的历史，以及男性和女性的前儿童兵，但没有绑架史的男性受试者。(C)2012年青少年健康和医学协会。All rights reserved.
Purpose: As we build the evidence base of interventions for depression among war-affected youth, it is critical to understand factors moderating treatment outcomes. The current study investigated how gender and history of abduction by Lord's Resistance Army rebels moderated treatment outcomes for war-affected youth.Methods: The study-a three-armed, randomized, controlled trial-was conducted with internally displaced war-affected adolescents in northern Uganda. Participants with significant depression symptoms (N = 304; 57% female; 14-17 years of age) were randomly assigned to an interpersonal psychotherapy group (IPT-G), a creative play/recreation group, or a wait-list control condition. Secondary analyses were conducted on data from this randomized controlled trial.Results: A history of abduction by Lord's Resistance Army rebels was reported by 42% of the sample. Gender and abduction history interacted to moderate the effectiveness of IPT-G for the treatment of depression. In the IPT-G intervention arm, treatment effectiveness was greatest among female subjects without an abduction history, with effect size = 1.06. IPT-G was effective for the treatment of depression for both male and female subjects with a history of abduction (effect size = .92 and .50, respectively). Male subjects with no abduction history in IPT-G showed no significant improvement compared with those in the control conditions.Conclusions: Abduction history and gender are potentially important moderators of treatment effects, suggesting that these factors need to be considered when providing interventions for war-affected youth. IPT-G may be an effective intervention for female subjects without an abduction history, as well as for both male and female former child soldiers, but less so for male subjects without an abduction history. (C) 2012 Society for Adolescent Health and Medicine. All rights reserved.