Visual slow brain potentials in children with attention deficit disorder.
Visual slow brain potentials in children with attention deficit disorder.
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注意力缺陷障碍儿童的视觉迟缓脑电位。
DOI：
10.1007/bf02691280
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发表时间：
1994
期刊：
影响因子：
--
通讯作者：
Dykman,RA
中科院分区：
文献类型：
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作者：
Newton,JE;Oglesby,DM;Ackerman,PT;Dykman,RA
我们使用两种刺激反应时间范式，以及两种独立的奖励条件（偶然和非偶然），比较了 144 名注意力缺陷障碍 (ADD) 儿童和 30 名正常对照儿童的慢波脑电位 (ERP)。本文回顾了 900 毫秒视觉警告刺激期间的发现。正如我们所预期的那样，基于 Forth 和 Hare (1989) 以及 Raine、Venables 和 Williams (1990) 的 ERP 工作以及我们自己实验室之前的工作，在偶然奖励条件下但在非偶然条件下，在 ERP 复合体的负慢波部分中发现了组间差异。在偶然奖励条件下，患有注意力缺陷障碍（ADDHA）的攻击性多动受试者（ADDHA）与非攻击性受试者（包括对照受试者）的区别在于：（1）额中央负性更大（640-900毫秒慢波）和（2）右顶叶比左顶叶更大负性（430-750毫秒慢波）。与对照（CONTR）受试者相比，所有ADD亚组都表现出更大的慢波在偶然奖励条件下，枕骨中线电极部位的波负性（700-900 毫秒）。这可以部分解释为 ERP 对 IQ 的影响，反映了 ADD 亚组和对照组之间的 IQ 差异。这些慢波发现似乎与这些儿童的注意力问题有关。它们是根据抑制/去抑制和食欲激活的心理生物学模型进行讨论的。
Using a two-stimulus reaction time paradigm, with two separate reward conditions (contingent and noncontingent), we compared slow wave brain potentials (ERPs) in 144 children with attention deficit disorder (ADD) and 30 normal control children. This article reviews the findings during the 900 msec visual warning stimulus.As we had expected, based on ERP work of Forth and Hare (1989) and Raine, Venables and Williams (1990), and on previous work from our own laboratory, the group differences were found in the negative slow wave portions of the ERP complex during the contingent reward condition but not during the noncontingent condition. Aggressive hyperactive subjects with attention deficit disorder (ADDHA) were discriminated from nonaggressive subjects (including control subjects) during the contingent reward condition in the following ways: (1) greater fronto-central negativity (640–900 msec slow wave) and (2) greater right parietal than left parietal negativity (430–750 msec slow wave).All ADD subgroups, when compared to control (CONTR) subjects, showed greater slow wave negativity (700–900 msec) at the midline occipital electrode site during the contingent reward condition. This could be explained in part as an IQ effect on ERPs reflecting the IQ difference between the ADD subgroups and the controls.These slow wave findings seem to relate to attentional problems of these children. They are discussed in terms of a psychobiological model of inhibition/disinhibition and appetitive activation.