A review of the risks and disease transmission associated with aerosol generating medical procedures.

A review of the risks and disease transmission associated with aerosol generating medical procedures.
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DOI:
10.1177/1757177409106456
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发表时间:
2009-01-01
影响因子:
1.2
通讯作者:
Bennett, A.
Bennett, A.
中科院分区:
其他
文献类型:
--
作者:
Davies, A.;Thomson, G.;Bennett, A.

文献摘要

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几种医疗程序,包括支气管镜检查、插管和无创通气,经常用于呼吸系统疾病的治疗或诊断,已被确定为潜在的“气溶胶产生”。人们认为,“气溶胶产生”过程(“AGP”)的性质导致感染性气溶胶超出了患者咳嗽、呼吸或说话通常释放的量,给任何靠近患者的医护人员带来了更大的风险。假人上的烟雾模型提供了可能的气溶胶行为的视觉图像,并指出了可能的传播区域。然而,它们不一定代表呼吸气溶胶和其中包含的任何感染性颗粒的行为。尚未对AGP进行定量研究。支气管镜检查和痰液诱导与结核病的医院传播有关,已经制定了指南,描述了在进行此类程序时应采用的适当通风、隔离和呼吸保护。围绕AGP的不确定性使得难以构建有效的感染控制政策。保护医护人员至关重要。然而,在大流行期间,资源可能会捉襟见肘。因此,必须澄清这些程序是否确实产生气溶胶。
Several medical procedures, including bronchoscopy, intubation, and non-invasive ventilation, frequently used in the treatment or diagnosis of respiratory diseases, have been identified as potentially 'aerosol generating'. It is thought that the nature of the 'aerosol generating' procedure ('AGP') results in an infectious aerosol beyond that which would normally be released by a patient coughing, breathing, or talking, presenting an increased risk to any healthcare worker in proximity to the patient. Smoke models on dummies have provided a visual image of possible aerosol behaviour and indicate a possible zone of transmission. However, they are not necessarily representative of the behaviour of a respiratory aerosol and any infectious particles contained therein. No quantitative study has yet been carried out on AGPs. Bronchoscopy and sputum induction have been associated with nosocomial transmission of tuberculosis, and guidelines have been produced describing the appropriate ventilation, isolation and respiratory protection that should be applied when carrying out such procedures. The uncertainty surrounding AGPs makes it difficult to construct effective infection control policy. The protection of healthcare workers is paramount. However, during a pandemic, resources may be stretched. Therefore it is important to clarify whether these procedures do generate aerosols.