Fluorinated Graphene for Promoting Neuro-Induction of Stem Cells

Fluorinated Graphene for Promoting Neuro-Induction of Stem Cells
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DOI:
10.1002/adma.201200846
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发表时间:
2012-08-16
期刊:
影响因子:
29.4
通讯作者:
Loh, Kian Ping
Loh, Kian Ping
中科院分区:
材料科学1区
文献类型:
--
作者:
Wang, Yu;Lee, Wong Cheng;Loh, Kian Ping

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基质的表面工程提供了在分子水平上控制细胞生理功能的可能性。氟化石墨烯促进MSC向神经元谱系分化。使用氟化石墨烯上的印刷聚二甲基硅氧烷通道阵列的细胞排列进一步增强了MSC的神经诱导,即使在没有化学诱导剂的情况下。
Surface engineering of substrates offers the possibility of controlling the physiological functions of cells at the molecular level. Fluorinated graphene promotes the differentiation of MSCs towards neuronal lineages. Cell alignment using printed polydimethylsiloxane channel arrays on fluorinated graphene further enhances the neuro-induction of MSCs even in the absence of chemical inducers.