Heparin-Induced Thrombocytopenia

Heparin-Induced Thrombocytopenia
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DOI:
10.1056/nejmcp1411910
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发表时间:
2015-07-16
影响因子:
158.5
通讯作者:
Greinacher, Andreas
Greinacher, Andreas
中科院分区:
医学1区
文献类型:
--
作者:
Greinacher, Andreas

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一名64岁的妇女因心内膜炎住院,在接受静脉注射抗生素治疗时病情临床稳定,血小板计数从住院第7天的161,000/立方毫米下降到第9天的60,000/立方毫米。自入院以来,她一直接受低分子量肝素治疗,剂量为每天40 mg。她的情况应该如何进一步评估和治疗?
A 64-year-old woman who is hospitalized with endocarditis and whose condition is clinically stable while she is receiving intravenous antibiotic agents has had a decrease in platelet count from 161,000 per cubic millimeter on day 7 of hospitalization to 60,000 per cubic millimeter on day 9. She has been receiving low-molecular-weight heparin at a dose of 40 mg per day since admission. How should her case be further evaluated and treated?