MASSETER INHIBITORY PERIODS AND SENSATIONS EVOKED BY ELECTRICAL TOOTH-PULP STIMULATION
MASSETER INHIBITORY PERIODS AND SENSATIONS EVOKED BY ELECTRICAL TOOTH-PULP STIMULATION
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DOI：
10.1016/0304-3959(81)90041-5
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发表时间：
1981-01-01
期刊：
影响因子：
7.4
通讯作者：
GRACELY, RH
中科院分区：
文献类型：
--
作者：
MCGRATH, PA;SHARAV, Y;GRACELY, RH
对 30 名受试者的咬肌抑制期和牙髓电刺激引起的感觉进行了评估。对上中切牙施加五种强度的电刺激，产生从低于感觉检测阈值到超阈值疼痛的不同感觉。在每个刺激强度处，施加一串 30、1 毫秒、脉冲间间隔为 2 秒的阴极脉冲。将固定刺激强度下 30 个脉冲引起的平均咬肌活动与引起的感觉质量进行比较。咬肌抑制期的阈值与个体对牙髓刺激的检测阈值大致一致。不同的刺激强度产生咬肌抑制期的三种配置（单次、双次和合并）。没有特定的结构与疼痛感明确相关。刺激强度的增加会引起咬肌抑制期的结构和产生的感觉质量的变化。卡方分析显示，咬肌抑制期配置之间存在显着但逐渐减弱的关联。一项关于麻醉镇痛药芬太尼作用的双盲研究也证明了感觉质量与咬肌抑制期配置之间关联的弱点。尽管使用芬太尼后非疼痛和疼痛感觉的强度显着降低，但咬肌抑制期没有变化。咬肌抑制期不能被认为是疼痛的可靠相关因素。反射性咬肌抑制通过三叉神经脑干感觉复合体中的通路起作用，该通路与阿片类药物对疼痛的抑制无关。
The masseter inhibitory period and sensations evoked by electrical tooth pulp stimulation were assessed in 30 human subjects. Five intensities of electrical stimuli, producing sensations varying from below sensory detection threshold to suprathreshold pain, were applied to upper central incisors. At each stimulus intensity a train of 30, 1 ms, cathodal pulses with an interpulse interval of 2 s was applied. The averaged masseter activity evoked by the 30 pulses at a fixed stimulus intensity was compared to the quality of the sensation elicited. The threshold for the masseter inhibitory period coincided approximately with an individual''s detection threshold for the tooth pulp stimulation. Three configurations of masseter inhibitory periods (single, double and merged) were produced by different stimulus intensities. No particular configuration was associated unequivocally with pain sensation. Increases in stimulus intensity evoked changes both in the configuration of the masseter inhibitory period and in the quality of the sensation produced. Chi square analyses showed significant, but progressively weaker, associations between: masseter inhibitory period configuration. The weakness of the association between the quality of sensation and masseter inhibitory period configuration also was demonstrated in a double-blind study of the effects of a narcotic analgesic, fentanyl. Although the strengths of non-pain and pain sensations were reduced significantly after fentanyl, there were no changes in the masseter inhibitory period. The masseter inhibitory period cannot be considered a reliable correlate of pain. The reflex masseter inhibition acts via pathways in the trigeminal brain stem sensory complex that are independent of opiate suppression of pain.