THE CHANGING PANORAMA OF CEREBRAL-PALSY IN SWEDEN .5. THE BIRTH YEAR PERIOD 1979-82
THE CHANGING PANORAMA OF CEREBRAL-PALSY IN SWEDEN .5. THE BIRTH YEAR PERIOD 1979-82
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DOI：
10.1111/j.1651-2227.1989.tb11071.x
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发表时间：
1989-03-01
期刊：
影响因子：
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通讯作者：
VONWENDT, L
中科院分区：
文献类型：
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作者：
HAGBERG, B;HAGBERG, G;VONWENDT, L
据报道，1979-82 年这四年间出生的瑞典婴儿中脑瘫 (CP) 的患病率与 1959-78 年这 20 年期间出生的婴儿的患病率相关。 1979-82年，这一数字为每1000名活产儿2.17人，其中足月儿为1.23人，早产儿为0.94人，这意味着自20世纪70年代初以来的上升趋势持续存在。最明显的上升是在患有痉挛/共济失调性双侧瘫痪的早产儿亚组中，从 1967-70 年期间的每 100 个活产 0.18 个增加到 1979-82 年的 0.67 个。早产儿脑瘫儿的运动障碍严重程度以及智力低下、婴儿脑积水和癫痫的相对发生率同期依次升高。 1967-82 年期间，足月婴儿的 CP 活产率略有增加，但不显着。 1967-82 年期间，所有出生体重组中每 1000 名第一周存活新生儿中出生体重特定的 CP 患病率均有所增加，出生体重低于 1500 克和超过 2500 克的儿童显着增加。脑瘫患病率的上升伴随着围产期死亡率的平行下降，特别是早产儿。在 20 世纪 80 年代，严重多残、极早产儿（仅在 20 世纪 60 年代和 70 年代出生的 CP 儿童中罕见）已成为人们关注的问题。
The prevalence of cerebal palsy (CP) in Swedish infants born in the four-year period 1979-82 is reported and related to the prevalence in infants born during the twenty-year period 1959-78. In 1979-82 it was 2.17 per 1000 livebirths, 1.23 for children born at term and 0.94 for preterms, which means that the rising trend since the beginning of the 1970s persisted. The most pronounced rise, from 0.18 per 100 livebirths in the period 1967-70 to 0.67 in 1979-82 was found in the subgroup of preterms with spastic/ataxic diplegia. The severity of motor disability and the relative frequency of mental retardation, infantile hydrocephalus and epilepsy among preterm CP children successively increased over the same period of time. The livebirth prevalence of CP in terms infants increased slightly but non-significantly during the period 1967-82. The birthweight-specific prevalence of CP per 1000 newborns surviving the first week increased in all birthweight groups during the period 1967-82, significantly for birthweights below 1500 g and over 2500 g. The rising prevalence of CP was concomitant with a parallel fall in perinatal mortality, especially in very preterm infants. In the 1980s, severely multi-handicapped, very preterm children, only exceptionally seen among CP children born in the 1960s and 1970s, has become a matter of concern.