Comparative mitochondrial proteomic analysis of human large cell lung cancer cell lines with different metastasis potential

Comparative mitochondrial proteomic analysis of human large cell lung cancer cell lines with different metastasis potential
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不同转移潜能人大细胞肺癌细胞系的线粒体蛋白质组学比较分析

DOI:
10.1111/1759-7714.13052
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发表时间:
2019-04
期刊:
影响因子:
2.9
通讯作者:
Zhou Qinghua
Zhou Qinghua
中科院分区:
医学3区
文献类型:
--
作者:
Liu Zhenkun;Xu Song;Li Lu;Zhong Xiaorong;Chen Chun;Fan Yaguang;Shen Wang;Zu Lingling;Xue Feng;Wang Min;Zhou Qinghua

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肺癌是一种高度侵袭性的癌症,预后差,易发生远处转移,但目前尚无临床公认的早期诊断和预测肺癌转移的生物标志物。我们试图鉴定不同的线粒体蛋白图谱,并了解肺癌转移的分子机制。
Lung cancer is a highly aggressive cancer with a poor prognosis and is associated with distant metastasis; however, there are no clinically recognized biomarkers for the early diagnosis and prediction of lung cancer metastasis. We sought to identify the differential mitochondrial protein profiles and understand the molecular mechanisms governing lung cancer metastasis.
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