Registration of a CT-like atlas to fluoroscopic X-ray images using intensity correspondences
Registration of a CT-like atlas to fluoroscopic X-ray images using intensity correspondences
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DOI：
10.1007/s11548-008-0264-z
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发表时间：
2008-12-01
影响因子：
3
通讯作者：
Joskowicz, Leo
中科院分区：
文献类型：
--
作者：
Hurvitz, Aviv;Joskowicz, Leo
目的提出一种基于术中图像的骨表面重建新方法并对其进行验证。材料和方法在术前阶段，我们构建了感兴趣解剖的ct样强度图谱。在术中阶段，我们将该图谱变形地登记到患者解剖的x线透视图像上。我们通过在寰椎骨表面和x射线图像中的投影之间建立明确的对应关系，迭代地完善寰椎到患者的注册。该方法的优点是使用ct质量的强度数据建立对应关系，消除了边缘检测问题，减少了不匹配问题。我们在两个数据集上验证了我们的方法：(1)体外干股骨；(2)由17张临床ct生成的数字化重建x线片，模拟真实的体内股骨。结果股骨图谱的平均表面近似误差为0.85±0.16 mm。在数字重建x线片上，平均表面重建误差为1.40±0.55 mm。对于干股骨，平均表面重建误差为1.44 mm。结论本方法在离体股骨重建方面达到了目前的水平。此外，结果表明，我们的方法是有效的现实模拟在体内的场景。
Objective We present a novel method for intraoperative image-based bone surface reconstruction and its validation.Materials and methods In the preoperative stage, we construct a CT-like intensity atlas of the anatomy of interest. In the intraoperative stage, we deformably register this atlas to fluoroscopic X-ray images of the patient anatomy. We iteratively refine the atlas-to-patient registration by establishing explicit correspondences between bone surfaces in the atlas and their projections in the X-ray images. The advantage of our method is its use of CT-quality intensity data for correspondence establishment, which eliminates the edge-detection problem and diminishes the miscorrespondence problem. We validate our method on two datasets: (1) an in vitro dry femur; (2) Digitally Reconstructed Radiographs, which were generated from 17 clinical CTs, and simulate realistic in vivo femurs.Results The mean surface approximation error of our femur atlaswas 0.85 +/- 0.16 mm. On Digitally Reconstructed Radiographs, the mean surface reconstruction error was 1.40 +/- 0.55 mm. On a dry femur, the mean surface reconstruction error was 1.44 mm.Conclusion The results show that our reconstruction method is on par with the state of the art in reconstruction of ex vivo femurs. In addition, the results demonstrate that our method is effective in realistic simulations of the in vivo scenario.