RIBOSOMAL-RNA SEQUENCE SUGGESTS MICROSPORIDIA ARE EXTREMELY ANCIENT EUKARYOTES
RIBOSOMAL-RNA SEQUENCE SUGGESTS MICROSPORIDIA ARE EXTREMELY ANCIENT EUKARYOTES
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DOI：
10.1038/326411a0
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发表时间：
1987-03-26
期刊：
影响因子：
64.8
通讯作者：
WOESE, CR
中科院分区：
文献类型：
--
作者：
VOSSBRINCK, CR;MADDOX, JV;WOESE, CR
微孢子虫是一组不寻常的专性寄生原生生物，它们感染各种各样的其他真核生物，包括脊椎动物、节肢动物、软体动物、环节动物、线虫、刺胞动物，甚至各种纤毛虫、粘孢子虫和gregarines1。它们具有许多不寻常的细胞学和分子特征。它们的核分裂被认为是连续的2，它们没有核糖体3，它们的核糖体和核糖体RNA被报道为原核大小的4，5，它们的核糖体大亚基不含5.8S rRNA 6。微孢子虫的独特性可能反映了它们的系统发育位置，因为比较序列分析表明，微孢子虫的小亚基rRNA比任何已知的真核生物18S rRNA序列更不同于其他真核生物。我们的结论是，谱系导致微孢子虫分支很早，从导致其他真核生物。
The microsporidia are a group of unusual, obligately parasitic protists that infect a great variety of other eukaryotes, including vertebrates, arthropods, molluscs, annelids, nematodes, cnidaria and even various ciliates, myxosporidia and gregarines1. They possess a number of unusual cytological and molecular characteristics. Their nuclear division is considered to be primitive2, they have no mitochondria3, their ribosomes and ribosomal RNAs are reported to be of prokaryotic size4,5and their large ribosomal subunit contains no 5.8S rRNA6. The uniqueness of the microsporidia may reflect their phylogenetic position, because comparative sequence analysis shows that the small subunit rRNA of the microsporidiumVairimorpha necatrix7,8is more unlike those of other eukaryotes than any known eukaryote 18S rRNA sequence. We conclude that the lineage leading to microsporidia branched very early from that leading to other eukaryotes.