Analyses of programmed cell death in dendritic cells.
Analyses of programmed cell death in dendritic cells.
复制标题
树突状细胞程序性细胞死亡的分析。
DOI：
10.1007/978-1-62703-290-2_6
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发表时间：
2013
期刊：
影响因子：
--
通讯作者：
Wang,Jin
中科院分区：
文献类型：
--
作者：
Chen,Min;Huang,Lily;Wang,Jin
树突状细胞（Dendritic cells，DCs）是一种专职的抗原提呈细胞，可调节先天性和适应性免疫应答。DCs的程序性细胞死亡在维持DCs的稳态和调节免疫应答中起重要作用。这里描述了测量DC的自发性和T细胞介导的细胞死亡率的方法。这些程序可以适用于研究树突状细胞死亡的诱导在不同的免疫反应的设置。
Dendritic cells (DCs) are professional antigen-presenting cells that can regulate both innate and adaptive immune responses. Programmed cell death of DCs plays an important role in maintaining the homeostasis of DCs and in the regulation of immune responses. Methods to measure the rate of spontaneous and T cell-mediated cell death of DCs are described here. These procedures can be adapted to study the induction of dendritic cell death in different settings of immune responses.