Audiological profile of asymptomatic Covid-19 PCR-positive cases
Audiological profile of asymptomatic Covid-19 PCR-positive cases
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DOI：
10.1016/j.amjoto.2020.102483
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发表时间：
2020-05-01
影响因子：
2.5
通讯作者：
Mustafa, M. W. M.
中科院分区：
文献类型：
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作者：
Mustafa, M. W. M.
目标：本研究比较了无症状COVID-19 PCR阳性病例和正常非感染受试者的瞬态诱发耳声发射（TEOAE）幅度和纯音听力阈值。方法：20例确诊为COVID-19阳性且无该病毒感染的已知症状的病例组成测试组。他们的年龄在20到50岁之间，以避免任何与年龄相关的听力影响。有明确COVID-19感染症状的患者以及有听力损失史或任何已知听力损失原因史的患者被排除在检查样本之外。结果：实验组的高频纯音听阈和TEOAE振幅明显低于对照组。结论：COVID-19感染尽管无症状，但仍可能对耳蜗毛细胞功能产生有害影响。这些影响的机制需要进一步研究。
Objective: The current study compared the amplitude of transient evoked otoacoustic emissions (TEOAEs) and thresholds of pure-tone audiometry between asymptomatic COVID-19 PCR-positive cases and normal non-infected subjects.Methods: Twenty cases who were confirmed positive for COVID-19 and had none of the known symptoms for this viral infection formed the test group. Their age ranged between 20 and 50 years to avoid any age-related hearing affection. Patients who had definite symptoms of COVID-19 infection as well as those who had a history of hearing loss or a history of any known cause of hearing loss were excluded from the examined sample. TEOAEs amplitude was measured for all participants.Results: The high frequency pure-tone thresholds as well as the TEOAE amplitudes were significantly worse in the test group.Conclusions: COVID-19 infection could have deleterious effects on cochlear hair cell functions despite being asymptomatic. The mechanism of these effects requires further research.