Study on Chemical Constituents of Semen Pharbitidis
Study on Chemical Constituents of Semen Pharbitidis
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DOI：
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发表时间：
2004
影响因子：
4.6
通讯作者：
Chen Li
中科院分区：
文献类型：
--
作者：
Chen Li
目的：研究五味子中具有通便作用的有效成分，建立其质量标准。方法：采用硅胶和Sephadex LH-20对其进行分离纯化，并通过多种波谱数据确定其结构。结果：从70%乙醇提取物的正丁醇部分和乙酸乙酯部分分离得到8个化合物，分别鉴定为大黄素甲醚(Ⅰ)、大黄素(Ⅱ)、大黄酚(Ⅲ)、咖啡酸乙酯(Ⅳ)、咖啡酸(Ⅴ)，α-乙基-O-D-半乳糖)(Ⅵ)、胡萝卜苷(Ⅶ)，β-谷甾醇，Ⅷ)。结论：化合物Ⅰ，Ⅱ，Ⅲ，Ⅳ，Ⅴ，Ⅵ为首次从该属植物中分离得到。
AIM:To study the active constituents with the purgative action and to establish quality standard in Semen pharbitidis. METHOD: Separation and purification were performed on silica gel and sephadex LH-20,and the structures were elucidated by various spectroscopic data. RESULT: Eight compounds were isolated from n-Butanol fraction and ethyl acetate fraction of 70% ethanol extract,and identified as physcion(Ⅰ),emodin(Ⅱ),chrysophanol(Ⅲ),ethyl caffeate(Ⅳ),caffeic acid(Ⅴ),α-ethyl-O-D-galactopyran(Ⅵ),daucosterol(Ⅶ),β-sitosterol(Ⅷ),respectively. CONCLUSION: Compounds Ⅰ,Ⅱ,Ⅲ,Ⅳ,Ⅴ,Ⅵ were isolated from the genus Pharbitis for the first time.