AN IMPROVED SYNTHESIS OF 8-BROMO-2'-DEOXYGUANOSINE
AN IMPROVED SYNTHESIS OF 8-BROMO-2'-DEOXYGUANOSINE
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DOI：
10.1080/00397919308011257
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发表时间：
1993-01-01
影响因子：
2.1
通讯作者：
SURA, TP
中科院分区：
文献类型：
--
作者：
GANNETT, PM;SURA, TP
本文报道了一种合成8-溴-2-脱氧鸟苷的新方法。8-溴-2-脱氧鸟苷是合成DNA加合物8-氧-2 ′-脱氧鸟苷的关键中间体。该方法的优点是显著提高的产率和易于分离。
A new synthesis of 8-bromo-2-deoxyguanosine, a key intermediate in the synthesis of the mutagenic DNA adduct 8-oxo-2'-deoxyguanosine is described. The advantages of this method are significantly improved yields and ease of isolation.