STOICHIOMETRY OF NITROUS ACID DEAMINATIVE CLEAVAGE OF MODEL AMINO SUGAR GLYCOSIDES AND GLYCOSAMINOGLYCURONANS

STOICHIOMETRY OF NITROUS ACID DEAMINATIVE CLEAVAGE OF MODEL AMINO SUGAR GLYCOSIDES AND GLYCOSAMINOGLYCURONANS
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DOI:
10.1021/bi00803a005
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发表时间:
1970-01-01
期刊:
影响因子:
2.9
通讯作者:
CONRAD, HE
CONRAD, HE
中科院分区:
生物学3区
文献类型:
--
作者:
SHIVELY, JE;CONRAD, HE

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J. E. Shivelyf和。E.康拉德摘要:用亚硝酸处理N-脱酰氨基糖或其糖苷,得到醛或酮氧化水平的脱氨基单体产物的混合物。产物容易通过放射色谱法定量(Koeltzow,D. E、Epley,J.D.,康拉德,。E.(1968),Biochemistry 7,2920)。脱氨基混合物的组成随所讨论的氨基糖和氨基糖糖苷的异头构型而变化。
J. E. Shivelyf and. E. Conrad abstract: Treatment of N-deacylated amino sugars or their glycosides with nitrous acid yields a mixture of deaminated monomeric products at the aldehyde or ketone oxidation level. The products are readily quantitated by radiochromatography (Koeltzow, D. E., Epley, J. D., and Conrad,. E.(1968), Biochemistry 7, 2920). The composition of the deaminated mixture varies with the amino sugar in question and with the anomeric configuration of the amino sugar glycoside.